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Medulloblastoma

Medulloblastoma is a highly malignant primary brain tumor that originates in the cerebellum or posterior fossa.Originally considered to be a glioma, medulloblastoma is now known to be of the family of cranial primitive neuroectodermal tumors .Tumors that originate in the cerebellum are referred to as infratentorial because they occur below the tentorium, a thick membrane that separates the cerebral hemispheres of the brain from the cerebellum. Another term for medulloblastoma is infratentorial PNET. Medulloblastoma is the most common PNET originating in the brain.All PNET tumors of the brain are invasive and rapidly growing tumors that, unlike most brain tumors, spread through the cerebrospinal fluid and frequently metastasize to different locations in the brain and spine. (From the Wikpedia article Medulloblastoma.)

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Recent Publications on Medulloblastoma:

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Tissue factor mediates the HGF/Met-induced anti-apoptotic pathway in DAOY medulloblastoma cells.
The classical treatment scheme for medulloblastoma (MB) is based on a...
19th November, 2009
Laboratoire de Medecine Moleculaire, Universite du Quebec a Montreal, C.P. J Neurooncol. 2009 Nov 18.
DOI Direct Link
Large cell/anaplastic medulloblastoma: Outcome according to myc status, histopathological, and clinical risk factors.
PURPOSE: To evaluate the prognostic impact of large cell/anaplastic (LC/A)...
13th November, 2009
Department of Pediatrics, University of Wuerzburg, Wuerzburg, Germany; Pediatr Blood Cancer. 2009 Nov 11.
DOI Direct Link
Heterozygous germ-line mutations in the NBN gene predispose to medulloblastoma in pediatric patients.
The NBN (NBS1) gene belongs to a group of double-strand break repair...
13th November, 2009
Department of Medical Genetics, The Children's Memorial Health Institute, Acta Neuropathol. 2009 Nov 12.
DOI Direct Link
p53 regulates LIF expression in human medulloblastoma cells.
Medulloblastomas are highly malignant, poorly differentiated childhood...
13th November, 2009
Department of Biology, Yorkshire Cancer Research p53 Research Unit, J Neurooncol. 2009 Nov 12.
DOI Direct Link
Differential expression profiling between atypical teratoid/rhabdoid and medulloblastoma tumor in vitro and in vivo using microarray analysis.
OBJECTIVES: Atypical teratoid/rhabdoid tumor (AT/RT) and medulloblastoma...
11th November, 2009
Department of Neurological Surgery, Tri-Service General Hospital, National Childs Nerv Syst. 2009 Nov 10.
DOI Direct Link

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BioNews Results for Medulloblastoma:

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Couple visits D.C. to lobby for cancer research
News-Messenger:  Nov 20 2009 2:15AM Matching: medulloblastoma
US and European market for radiopharmaceuticals continues to gain momentum
News-Medical.Net:  Nov 20 2009 8:12AM Matching: medulloblastoma
Couple visits D.C. to lobby for cancer research
Port Clinton News Herald:  Nov 19 2009 5:05PM Matching: medulloblastoma
Medulloblastoma: Studies from Genentech, Inc. yield new data on medulloblastoma
NewsRX:  Nov 16 2009 7:10AM Matching: medulloblastoma
State trooper to run 33 miles to help friends dealing with cancer issues
Lafayette Journal & Courier:  Nov 13 2009 3:34PM Matching: medulloblastoma
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Medulloblastoma Patents:

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US Patent No.Title
7582726 VEGF receptor antagonists
7592332 Cytokine inhibitors
7592342 Quinoxaline derivatives as PI3 kinase inhibitors
7592422 Modified plasminogen activator inhibitor type-1 and methods based thereon
7595038 Methods of treatment using antibodies to follistatin-3

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BioPortfolio Ltd. offers e-mail and postal lists for Medulloblastoma scientists - we have details of around 508 individuals working on Medulloblastoma .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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