Metaplasia

:For the brachiopod genus, see Metaplasia .Metaplasia is the reversible replacement of one differentiated cell type with another mature differentiated cell type. The change from one type of cell to another is generally caused by some sort of abnormal stimulus. In simplistic terms, it is as if the original cells are not robust enough to withstand the new environment, and so they change into another type more suited to the new environment. If the stimulus that caused metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. Metaplasia is not synonymous with dysplasia and is not considered carcinogenesis. It is also contrasted with heteroplasia, which is the abnormal growth of cytologic and histologic elements without a stimulus.Heteroplasia and dysplasia are synonyms. (From the Wikpedia article Metaplasia.)

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Recent Publications on Metaplasia:
Comprehensive imaging of gastroesophageal biopsy samples by spectrally encoded confocal microscopy. BACKGROUND: Spectrally encoded confocal microscopy (SECM) is a high-speed...	20th November, 2009	Current affiliations: Wellman Center for Photomedicine (D.K., M.J.S.,	Gastrointest Endosc. 2009 Nov 16. DOI Direct Link
In Benign Barrett's Epithelial Cells, Acid Exposure Generates Reactive Oxygen Species That Cause DNA Double-Strand Breaks. Cells that sustain double-strand breaks (DSB) can develop genomic...	19th November, 2009	Department of Medicine, VA North Texas Health Care System and Harold C.	Cancer Res. 2009 Nov 17. DOI Direct Link
Primary retroperitoneal mucinous cystadenocarcinoma in a male patient: a case report. In the literature, 51 cases of primary retroperitoneal mucinous...	18th November, 2009	Surgery Unit "Clinique Chirurgicale C", University Hospital Ibn Sina Rabat	Cases J. 2009 Aug 17;2:7196. DOI Direct Link
Increased lysozyme expression in gastric biopsies with intestinal metaplasia and pseudopyloric metaplasia. Lysozyme is an innate enzyme with potent non-immunological antibacterial...	18th November, 2009	Gastrointestinal and Liver Pathology Research Laboratory, Department of	Int J Clin Exp Med. 2009 Sep 2;2(3):248-53.
Retained capsule endoscope leading to the identification of small bowel adenocarcinoma in a patient with undiagnosed Crohn disease. Small intestinal neoplasia is a rare condition that frequently presents a...	18th November, 2009	Department of Internal Medicine, Rhode Island Hospital, Warren Alpert	Ann Diagn Pathol. 2009 Dec;13(6):390-3. Epub 2009 Sep 18. DOI Direct Link
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BioNews Results for Metaplasia:
Editorial: One small step for metaplasia, but one giant leap for biomarkers is needed	Bioscience Technology Online:  Nov 7 2009 3:46AM Matching: metaplasia
Obesity, but not overweight, increases BE risk	MedWire News:  Oct 26 2009 1:20AM Matching: metaplasia
Chronic idiopathic myelofibrosis with myeloid metaplasia presenting as refractory ascites	MDLinx:  Oct 19 2009 10:37AM Matching: metaplasia
Scientists Identify Gene for Short Circuiting Excess Mucous in Lung Disease, Common Colds	U.S. Newswire:  Sep 15 2009 2:48AM Matching: metaplasia

Metaplasia Patents:
US Patent No.	Title
7538859	Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto
7567349	Speckle reduction in optical coherence tomography by path length encoded angular compounding
7566791	Substituted 3-carbonyl-1h-indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
7566536	WNT-regulated cytokine-like polypeptide and nucleic acids encoding same
7564550	Fluorescence polarization imaging devices and methods
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