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Narcolepsy

Narcolepsy is a neurological condition most characterized by Excessive Daytime Sleepiness . A narcoleptic will most likely experience disturbed nocturnal sleep, which is often confused with insomnia, and disorder of REM or rapid eye movement sleep. It is one of the dyssomnias. A narcoleptic may also sleep at any random time.The term narcolepsy derives from the French word narcolepsie created in 1880 by the French physician Jean-Baptiste-Édouard Gélineau by combining the Greek narke numbness, stupor and lepsis attack, seizure. (From the Wikpedia article Narcolepsy.)

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Recent Publications on Narcolepsy:

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Psychosocial and intellectual functioning in childhood narcolepsy.
Purpose: This study reports the psychological assessment of 12 children...
9th July, 2008
Fraser of Allander Neurosciences Unit, Glasgow, UK. Dev Neurorehabil. 2008 Apr 1;:1-8.
DOI Direct Link
Abnormal sleep and sleepiness in Parkinson's disease.
PURPOSE OF REVIEW: Sleep problems are frequent and disabling in patients...
9th July, 2008
Sleep Disorders Unit, Pitie-Salpetriere Hospital, Assistance Curr Opin Neurol. 2008 Aug;24(4):472-7.
DOI Direct Link
The signalling profile of recombinant human orexin-2 receptor.
Orexin-A and orexin-B orchestrate their diverse central and peripheral...
5th July, 2008
Endocrinology & Metabolism Group, Clinical Sciences Research Institute, Cell Signal. 2008 May 27;.
DOI Direct Link
Armodafinil for excessive daytime sleepiness.
Armodafinil is the (R)-enantiomer of the wakepromoting compound modafinil...
4th July, 2008
Professor of Psychiatry and Behavioral Sciences, Director, Sleep and Drugs Today (Barc). 2008 Jun;44(6):395-414.
DOI Direct Link
Increased heart rate variability but normal resting metabolic rate in hypocretin/orexin-deficient human narcolepsy.
STUDY OBJECTIVES: We investigated autonomic balance and resting metabolic...
4th July, 2008
Department of Neurology and Clinical Neurophysiology, Leiden University J Clin Sleep Med. 2008 Jun 15;4(3):248-54.

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BioNews Results for Narcolepsy:

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Nicotine use and narcolepsy
News-Medical.Net:  Jun 10 2008 6:59AM Matching: narcolepsy
APSS: Smoking and Narcolepsy a Dangerous Combination
MedPage Today:  Jun 10 2008 4:23PM Matching: narcolepsy
Narcolepsy Drug Fights Cancer Fatigue
WebMD:  Jun 5 2008 4:18AM Matching: narcolepsy
Narcolepsy drug helps cancer-related fatigue: study
Therapeutics Daily:  Jun 2 2008 4:27PM Matching: narcolepsy
Narcolepsy drug helps cancer-related fatigue: study
Scientific American:  May 31 2008 10:14PM Matching: narcolepsy
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Narcolepsy Clinical Trials:

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A Safety and Effectiveness Study of a Single Dose of JNJ-17216498 in Patients With Narcolepsy
Narcolepsy Intervention: Drug: JNJ-17216498
An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue
Fibromyalgia, Primary
Modafinil for Fatigue in HIV/AIDS
HIV Infections;   Fatigue
Methylphenidate and Parkinson's Disease
Parkinson's Disease
Armodafinil for Fibromyalgia Fatigue
Fibromyalgia;   Fatigue

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Narcolepsy Patents:

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US Patent No.Title
7348323 Pyrrolo [2,3-c] pyridine derivatives
7365076 Substituted aryl cycloalkanol derivatives and methods of their use
7365077 Piperazine bis-amide derivatives and their use as antagonists of the orexin receptor
7365079 Azole derivatives
7368443 2,6-disubstituted piperidines and piperazine compounds

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Companies working in the area of Narcolepsy from Bioportfolio's Biocorporate database :

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Company Name

Sleep HealthCenters®, Inc.

It is estimated that at least 40 million Americans suffer from a chronic sleep disorder or intermittent sleep-related problem. Sleep deprivation is an unhealthy, dangerous and costly problem.Sleep...
www.sleephealth.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Narcolepsy scientists - we have details of around 270 individuals working on Narcolepsy .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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