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Natriuresis

Natriuresis is the process of excretion of sodium in the urine via action of the kidneys. Natriuresis is promoted by Brain and Atrial natriuretic peptides, and it is inhibited by chemicals such as aldosterone. Natriuresis lowers the concentration of sodium in the blood and also tends to lower blood volume because osmotic forces make water follow sodium out of the body's blood circulation and into the urine. Many diuretic drugs take advantage of this mechanism to treat medical conditions like hypernatremia and high blood pressure. Natural Disasters (From the Wikpedia article Natriuresis.)

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Recent Publications on Natriuresis:

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[Natriuretic peptides--their receptors and role in cardiovascular system]
Natriuretic peptides belong to a family of small proteins that play a...
10th July, 2008
Katedra i Zaklad Biofizyki Molekularnej i Medycznej, Uniwersytet Medyczny Postepy Biochem. 2008;54(1):35-42.
Acute angiotensin II infusions elicit pressure natriuresis in mice and reduce distal fractional sodium reabsorption.
Acute angiotensin II (Ang II) infusions into mice increase arterial...
9th July, 2008
Department of Physiology and Hypertension and Renal Center of Excellence, Hypertension. 2008 Jul;52(1):137-42. Epub 2008 May 26.
DOI Direct Link
Effect of acute unilateral renal denervation on renal hemodynamics in spontaneously hypertensive rats.
1 This study was undertaken to characterize the renal responses to acute...
5th July, 2008
School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, Auton Autacoid Pharmacol. 2008 Apr-Jul;28(2-3):87-94.
DOI Direct Link
Sodium Excretion in Response to Vasopressin and Selective Vasopressin Receptor Antagonists.
The mechanisms by which arginine vasopressin (AVP) exerts its antidiuretic...
4th July, 2008
*INSERM, Unite 872, and UMRS 872, Universite Paris Descartes, Centre de J Am Soc Nephrol. 2008 Jul 2;.
DOI Direct Link
Dietary salt induces transcription of the prostaglandin transporter gene in renal collecting ducts.
Prostaglandin E2(PGE2) activates its receptors on the renal collecting...
27th June, 2008
Medicine, Albert Einstein College of Medicine, Bronx, New York, United Am J Physiol Renal Physiol. 2008 Jun 25;.
DOI Direct Link

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Natriuresis Clinical Trials:

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Effect of Gene Variants on Dopamine Receptor Natriuretic Responses
Hypertension Interventions: Drug: fenoldopam;   Drug: Placebo
Evaluating the Relationship Between Inflammation, Genetics, and Stress in the Development of High Blood Pressure
Peripheral Dopamine in Postural Tachycardia Syndrome
Postural Tachycardia Syndrome;   Orthostatic Intolerance
Water Immersion in Right-Sided Heart Failure: A Pilot Study
Right Sided Cardiac Failure
Study to Assess Hemodynamic Effects, Safety and Tolerability of Chimeric Natriuretic Peptide (CD-NP) in Patients With Stabilized Acute Heart Failure (AHF)
Acute Decompensated Heart Failure

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Natriuresis Patents:

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US Patent No.Title
7034034 Substituted 2-cyclohexyl-4-phenyl-1H-imidazole derivatives
7125904 Peripherally-selective inhibitors of dopamine-.beta.-hydroxylase and method of their preparation
7132539 Melanocortin receptor ligands
7141547 Albumin fusion proteins comprising GLP-1 polypeptides
7153881 Compounds acting as melanocortin receptor ligands

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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