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NecrosisNecrosis is the name given to accidental death of cells and living tissue. It begins with cell swelling, chromatin digestion, and disruption of the plasma membrane and organelle membranes. Late necrosis is characterized by extensive DNA hydrolysis, vacuolation of the endoplasmic reticulum, organelle breakdown, and cell lysis. The release of intracellular content after plasma membrane rupture is the cause of inflammation in necrosis. In contrast to apoptosis, cleanup of cell debris by phagocytes of the immune system is generally more difficult, as the disorderly death generally does not send cell signals which tell nearby phagocytes to engulf the dying cell. This lack of signaling makes it harder for the immune system to locate and recycle dead cells which have died through necrosis than if the cell had undergone apoptosis. (From the Wikpedia article Necrosis.) Download PDF 
Recent Publications on Necrosis: |  |
Long catheter sign - a reliable bedside sign of incorrect positioning of Foley catheter in male spinal cord injury patients: a case report.
ABSTRACT: INTRODUCTION: Indwelling urethral catheter is often used in male... | 19th July, 2008
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| Cases J. 2008 Jul 17;1(1):43.
DOI Direct Link |
Are Prophylactic Antibiotics Really Ineffective in Reducing the Risk of Pancreatic Necrosis?
The serum cytokine levels (in particular interleukine-6 (IL-6) and tumour... | 19th July, 2008
| Department of Gastroenterology, and Hepatology, Kyoto University, Graduate
| Am J Gastroenterol. 2008 Jun 30;.
DOI Direct Link |
CD43 controls the intracellular growth of Mycobacterium tuberculosis through the induction of TNF-alpha-mediated apoptosis.
Establishment of Tuberculosis infection begins with the successful entry... | 19th July, 2008
| Department of Medicine, University of British Columbia, Canada.
| Cell Microbiol. 2008 Jul 9;.
DOI Direct Link |
Spontaneous In Vitro Transformation of Adult Neural Precursors into Stem-Like Cancer Cells.
Recent studies have found that cellular self-renewal capacity in brain... | 19th July, 2008
| Department of Neuropathology, Franz-Penzoldt-Center, University of
| Brain Pathol. 2008 Jul 10;.
DOI Direct Link |
Isolation and Characterization of Immunostimulatory Polysaccharide from an Herb Tea, Gynostemma pentaphyllum Makino.
Water-soluble polysaccharide from Gynostemma pentaphyllum herb tea (PSGP)... | 19th July, 2008
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| J Agric Food Chem. 2008 Jul 18;.
DOI Direct Link |
→View more research publications. |
Companies working in the area of Necrosis from Bioportfolio's Biocorporate database : |  |
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GenVec, Inc. (NASDAQ: GNVC) is a biopharmaceutical company developing novel gene-based therapeutic drugs and vaccines. Each of our gene-based therapeutic product candidates use a common patent...
www.genvec.com/ View full profile
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TECHNICLONE CORPORATION is engaged in the research and development of unique therapeutics for the treatment of cancer: The company utilizes innovative targeting technologies to develop products...
www.techniclone.com/ View full profile
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ENBREL is a type of protein called a tumor necrosis factor (TNF) blocker that blocks the action of a substance your body's immune system makes called TNF. People with an immune disease, such as...
www.enbrel.com/ View full profile
| | →View more Necrosis related companies. | BioPortfolio Ltd. offers e-mail and postal lists for Necrosis scientists - we have details of around 19087 individuals working on Necrosis .
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. |
