Neuroblastoma

Neuroblastoma is the most common extracranial solid cancer in infancy and childhood, with an annual incidence of about 650 new cases per year in the US. Close to 50 percent of neuroblastoma cases occur in children younger than two years old. It is a neuroendocrine tumor, arising from any neural crest element of the sympathetic nervous system or SNS. A branch of the autonomic nervous system, the SNS is a nerve network that carries messages from the brain throughout the body and is responsible for the fight-or-flight response and production of adrenaline or epinephrine. Its solid tumors, which take the form of a lump or mass, commonly begin in one of the adrenal glands, though they can also develop in nerve tissues in the neck, chest, abdomen, or pelvis. The cause of neuroblastoma is unknown, though most physicians believe that it is an accidental cell growth that occurs during normal development of the adrenal glands.Neuroblastoma is one of the rare human malignancies known to demonstrate spontaneous regression from an undifferentiated state to a completely benign cellular appearance. (From the Wikpedia article Neuroblastoma.)

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Recent Publications on Neuroblastoma:
Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents. BACKGROUND: Cancer stem cell theory suggests that the presence of tumor...	21st November, 2009	The Carman and Ann Adams Department of Pediatrics, Children's Research	Pediatr Blood Cancer. 2009 Nov 19. DOI Direct Link
Simultaneous analysis of neuroendocrine tumor markers by HPLC-electrochemical detection. A validated, high pressure liquid chromatographic (HPLC) method for...	21st November, 2009	Department of Chemical Pathology (Chromatography Section), National Health	J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 1. DOI Direct Link
Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives. Condensation of 9-chloro-2,4-(un)substituted acridines (1a-c) with various...	21st November, 2009	Department of Chemistry, Indian Institute of Technology-Roorkee, Roorkee	Eur J Med Chem. 2009 Nov 3. DOI Direct Link
A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells. ABSTRACT: BACKGROUND: The deposition of unconjugated bilirubin (UCB) in...	21st November, 2009		BMC Genomics. 2009 Nov 19;10(1):543. DOI Direct Link
The Death Effector Domains of Caspase-8 Induce Terminal Differentiation. The differentiation and senescence programs of metazoans play key roles in...	20th November, 2009	Department of Pathology, School of Medicine, University of California San	PLoS One. 2009 Nov 18;4(11):e7879. DOI Direct Link
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Press Releases About Neuroblastoma:
Reportlinker Adds World Market for Cancer Therapeutics and Biotherapeutics, 3rd. Edition, The Report	24th September, 2009	Reportlinker	-- SERMS The report includes market share by type of cancer and market share by company for each of the three major segments. It also includes statistical information for cancers by type
Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting	29th May, 2009	Bayer Healthcare Pharmaceuticals Inc.	WAYNE, N.J., May 29 /PRNewswire/ -- Bayer Healthcare Pharmaceuticals Inc. today announced that several studies evaluating the use of Leukine(R) (sargramostim) will be presented at the 2009 American
New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer	28th May, 2009	The Children's Hospital of Philadelphia	--In a First, Immunotherapy Works Against Neuroblastoma-- PHILADELPHIA, May 28 /PRNewswire-USNewswire/ -- A multicenter research team has announced encouraging results for an experimental therapy
Drilling Engineers Donate $35,000 to Texas Children's Hospital	15th December, 2008	American Association of Drilling Engineers	HOUSTON, Dec. 15 /PRNewswire/ -- The Houston Chapter of the American Association of Drilling Engineers (AADE) recently presented Texas Children's Hospital with a donation of $35,000 to
Scripps Translational Science Institute Contributes to Discovery of Predisposition Gene for Childhood Cancer	25th August, 2008	Scripps Translational Science Institute	SAN DIEGO, Aug. 25 /PRNewswire/ -- Researchers at Scripps Translational Science Institute (STSI) have contributed to a major genetic breakthrough -- the discovery of a gene responsible for the

BioNews Results for Neuroblastoma:
Cancer screening: What could it hurt? A lot, actually	Los Angeles Times:  Nov 21 2009 6:02AM Matching: neuroblastoma
Benefit raises money for child with cancer	Southwest Florida Herald Tribune:  Nov 20 2009 1:22PM Matching: neuroblastoma
Couple visits D.C. to lobby for cancer research	News-Messenger:  Nov 20 2009 2:15AM Matching: neuroblastoma
Cancer boy to meet football heroes this Saturday A five-year-old Northamptonshire boy who is battling cancer w	Northampton Evening Telegraph:  Nov 19 2009 8:08PM Matching: neuroblastoma
'Shagging for Bayler' event to benefit young cancer patient	The Item:  Nov 19 2009 2:55PM Matching: neuroblastoma
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Neuroblastoma Patents:
US Patent No.	Title
7608411	Prostaglandin receptor EP1
7611893	Metal-binding therapeutic peptides
7611910	Method for diagnosis of alzheimer's disease
7612032	Method for treating oncological diseases
7612033	Methods for delivering compounds into a cell
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