O6-Methylguanine-DNA Methyltransferase

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Recent Publications on O6-Methylguanine-DNA Methyltransferase:
Careful Exclusion of Non-neoplastic Brain Components is Required for an Appropriate Evaluation of O6-methylguanine-DNA Methyltransferase Status in Glioma: Relationship Between Immunohistochemistry and Methylation Analysis. Evaluation of O-methylguanine-DNA methyltransferase (MGMT) expression is...	27th June, 2008	*Laboratory of Molecular and Cellular Pathology, Hokkaido University	Am J Surg Pathol. 2008 Jun 19;. DOI Direct Link
Individual adjuvant therapy for malignant gliomas based on O6-methylguanine-DNA methyltransferase messenger RNA quantitation by real-time reverse-transcription polymerase chain-reaction. A new adjuvant therapy, individual adjuvant therapy (IAT), which is...	26th June, 2008	Department of Neurosurgery, Kawasaki Hospital, Ibaraki 313-8511, Japan.	Oncol Rep. 2008 Jul;20(1):165-71.
Validation of Real-Time Methylation-Specific PCR to Determine O6-Methylguanine-DNA Methyltransferase Gene Promoter Methylation in Glioma. Epigenetic silencing of the DNA repair protein O(6)-methylguanine-DNA...	17th June, 2008	OncoMethylome Sciences SA, Tour 5 GIGA (B34), +3, Avenue de l'Hopital 11,	J Mol Diagn. 2008 Jul;10(4):332-337. Epub 2008 Jun 13. DOI Direct Link
Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation. The DNA repair enzyme O(6)-methylguanine DNA methyltransferase (MGMT)...	14th June, 2008	Department of Pharmacology and Toxicology, Faculty of Medicine, University	Biochem Pharmacol. 2008 Jun 1;75(11):2100-11. Epub 2008 Mar 8. DOI Direct Link
A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis. The O(6)-methylguanine DNA methyltransferase (MGMT) gene encodes a DNA...	13th June, 2008	Department of Anatomy, University of Kiel, Olshausenstr. 40, 24098 Kiel,	Anal Biochem. 2008 Jun 1;377(1):62-71. Epub 2008 Mar 14. DOI Direct Link
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BioNews Results for O6-Methylguanine-DNA Methyltransferase:
Vical announces breakthrough in phase 1 trial of DNA Vaccines against pandemic influenza	PharmaBiz:  Jul 19 2008 6:11AM Matching: dna
Norgen Biotek Corp. Launches Four New Kits for the Purification of RNA and DNA from Plants and Fungi	Pharma Live:  Jul 18 2008 11:16PM Matching: dna
Norgen Biotek Corp. Launches Four New Kits for the Purification of RNA and DNA from Plants and Fungi	KRON4:  Jul 19 2008 6:32AM Matching: dna
Foreign DNA experts may probe sodomy charge against Ibrahim	Uzbekistan News:  Jul 19 2008 1:27AM Matching: dna
Norgen Biotek Corp. Launches Four New Kits for the Purification of RNA and DNA from Plants and Fungi	KOTA Territory News:  Jul 18 2008 8:37PM Matching: dna
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O6-Methylguanine-DNA Methyltransferase Clinical Trials:
Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors	Bone Marrow Suppression;   Brain and Central Nervous System Tumors;   Drug/Agent Toxicity by Tissue/Organ

O6-Methylguanine-DNA Methyltransferase Patents:
US Patent No.	Title
7229759	Highly sensitive method for the detection of cytosine methylation patterns
6046036	DNA sequences encoding fusions of DNA repair proteins and uses thereof
6200754	Inhibitors of alternative alleles of genes encoding products that mediate cell response to environmental changes
6465448	Methoxyamine potentiation of temozolomide anti-cancer activity
6635677	Methoxyamine combinations in the treatment of cancer
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