Odontogenesis

Odontogenesis is the formation and development of teeth. Tooth development can be divided into three overlapping phases. initiation, morphogenesis and histogenesis. During initiation, the oral epithelium folds inwards to form the tooth germs and the site of tooth develoment . Then undifferentiated mesenchymal cells migrates to the site of tooth formation and proliferates to determine the shape of the tooth during the morphogenesis phase. During histogenesis, differentiation of cells proceeds to give rise to the mature dental tissues.Tooth development is divided into roughly into 5 stages. These are the bud stage, cap stage, bell stage, dentinogenesis and amelogenesis. (From the Wikpedia article Odontogenesis.)

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Recent Publications on Odontogenesis:
WNT5A inhibits human dental papilla cell proliferation and migration. WNT proteins are a large family of cysteine-rich secreted molecules that...	3rd November, 2009	West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan,	Biochem Biophys Res Commun. 2009 Oct 28. DOI Direct Link
Primary cilia of odontoblasts: possible role in molar morphogenesis. A primary cilium, a sensory organelle present in almost every vertebrate...	3rd November, 2009	University of Lyon, Villeurbanne, F-69100, France.	J Dent Res. 2009 Oct;88(10):910-5. DOI Direct Link
Runx2, osx, and dspp in tooth development. The transcription factors Runx2 and Osx are necessary for osteoblast and...	3rd November, 2009	Department of Pediatric Dentistry, TheUniversity of Texas Health Science	J Dent Res. 2009 Oct;88(10):904-9. DOI Direct Link
The impact of fluoride on ameloblasts and the mechanisms of enamel fluorosis. Intake of excess amounts of fluoride during tooth development cause enamel...	3rd November, 2009	Department of Oral Cell Biology, ACTA, University of Amsterdam and VU	J Dent Res. 2009 Oct;88(10):877-93. DOI Direct Link
Craniofacial characteristics of patients with heart disease. INTRODUCTION: Children with congenital heart disease commonly experience...	30th October, 2009	Department of Orthodontics, State University of Rio de Janeiro, Rio de	Am J Orthod Dentofacial Orthop. 2009 Oct;136(4):554-8. DOI Direct Link
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Odontogenesis Patents:
US Patent No.	Title
7588936	Generating teeth from bone marrow cells
5240415	Dental bleach system having separately compartmented fumed silica and hydrogen peroxide and method of using
5766011	Dental bleaching composition and method
5874562	Nucleic acid encoding developmentally-regulated endothelial cell locus-1
5877281	Developmentally-regulated endothelial cell locus-1
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