Odontogenesis

Odontogenesis is the formation and development of teeth. Tooth development can be divided into three overlapping phases. initiation, morphogenesis and histogenesis. During initiation, the oral epithelium folds inwards to form the tooth germs and the site of tooth develoment . Then undifferentiated mesenchymal cells migrates to the site of tooth formation and proliferates to determine the shape of the tooth during the morphogenesis phase. During histogenesis, differentiation of cells proceeds to give rise to the mature dental tissues.Tooth development is divided into roughly into 5 stages. These are the bud stage, cap stage, bell stage, dentinogenesis and amelogenesis. (From the Wikpedia article Odontogenesis.)

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Recent Publications on Odontogenesis:
Structure and development of first-generation teeth in the cichlid Hemichromis bimaculatus (Teleostei, Cichlidae). In order to build a reference system to assess results of ongoing in vitro...	17th July, 2008	Instituut voor Dierkunde, Universiteit Gent, Belgium.	Tissue Cell. 1997 Dec;29(6):679-97.
Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signaling. Here we take the first look at cellular dynamics and molecular signaling...	17th July, 2008	Department of Oral Health Sciences, University of British Columbia,	Dev Biol. 2008 Jul 1;319(1):132-45. Epub 2008 Mar 15. DOI Direct Link
Immunoexpression of integrins in ameloblastoma, adenomatoid odontogenic tumor, and human tooth germs. The expression of integrins alpha2beta1, alpha3beta1, and alpha5beta1 in...	25th June, 2008	Department of Oral Pathology, Dentistry School, University of Pernambuco,	Int J Surg Pathol. 2008 Jul;16(3):277-85. DOI Direct Link
A regulatory relationship between Tbx1 and FGF signaling during tooth morphogenesis and ameloblast lineage determination. The Tbx1 gene is a transcriptional regulator involved in the DiGeorge...	24th June, 2008	Department of Orofacial Development and Structure, Institute of Oral	Dev Biol. 2008 Apr 16;. DOI Direct Link
Comparative qualitative and quantitative assessment of biomineralization of tooth development in man and zebrafish (Danio rerio). It was the aim of this study to investigate the distribution of Ca, P, and...	24th June, 2008	Faculty of Dental Medicine, University of Witten/Herdecke, Witten,	Anat Rec (Hoboken). 2008 May;291(5):571-6. DOI Direct Link
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Odontogenesis Patents:
US Patent No.	Title
7384652	Complexed-acidic-phospholipid-collagen composites for bone induction
5240415	Dental bleach system having separately compartmented fumed silica and hydrogen peroxide and method of using
5766011	Dental bleaching composition and method
5874562	Nucleic acid encoding developmentally-regulated endothelial cell locus-1
5877281	Developmentally-regulated endothelial cell locus-1
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