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Oligoribonucleotides

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Recent Publications on Oligoribonucleotides:

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Synthesis of oligoribonucleotides containing N6-alkyladenosine and 2-methylthio-N6-alkyladenosine.
The N(6)-alkyladenosines and 2-methylthio-N(6)-alkyladenosines are the...
10th July, 2008
Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Curr Protoc Nucleic Acid Chem. 2004 Sep;Chapter 4:Unit 4.23.
DOI Direct Link
Delivery of small interfering RNA. A review and an example of application to a junction oncogene.
RNA interference strategies using small interfering RNA is one of the most...
3rd July, 2008
CNRS UMR 8121, Universite Paris-Sud, Institut Gustave Roussy Villejuif, Tumori. 2008 Mar-Apr;94(2):254-63.
The RNase E/G-type endoribonuclease of higher plants is located in the chloroplast and cleaves RNA similarly to the E. coli enzyme.
RNase E is an endoribonuclease that has been studied primarily in...
17th June, 2008
Department of Biology, Technion-Israel Institute of Technology, Haifa RNA. 2008 Jun;14(6):1057-68. Epub 2008 Apr 25.
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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.
The safe and effective delivery of RNA interference (RNAi) therapeutics...
5th June, 2008
David H. Koch Institute for Integrative Cancer Research, Massachusetts Nat Biotechnol. 2008 May;26(5):561-9. Epub 2008 Apr 27.
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Preparation of 5'-silyl-2'-orthoester ribonucleosides for use in oligoribonucleotide synthesis.
The recent discovery that small interfering RNAs (siRNAs) induce gene...
5th June, 2008
Dharmacon Inc., Lafayette, Colorado, USA. Curr Protoc Nucleic Acid Chem. 2004 May;Chapter 2:Unit 2.10.
DOI Direct Link

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Oligoribonucleotides Clinical Trials:

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An Evaluation of the Efficacy and Safety of TOLAMBA™ for Ragweed-Allergic Rhinitis in an Environmental Exposure Chamber
Rhinitis, Allergic, Seasonal

Oligoribonucleotides Patents:

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US Patent No.Title
7288372 Methods for the preparation of chemically misaminoacylated tRNA via protective groups
7314923 Nucleoside and oligonucleotide analogues
7316915 Bak binding protein, DNA encoding the protein, and methods of use thereof
7319003 Arrays of probes for positional sequencing by hybridization
7320965 Compositions and methods for inhibiting expression of Huntingtin gene

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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