Recent Publications on Oncogene Protein P21Ras: |  |
The nitric oxide-sensitive p21Ras-ERK pathway mediates S-nitrosoglutathione-induced apoptosis.
p21Ras protein plays a critical role in cellular signaling that induces...
Direct Link | 15th May, 2008
| Departamento de Bioquimica/Biologia Molecular, Centro Interdisciplinar de
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| P21ras and phosphorylated extracellular signal-regulated protein kinase are highly expressed in vascular smooth muscle cells of hypertensive rats.
| 25th April, 2008
| Institute of Immunopathology, School of Life Science and Technology, Xi'an
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What is the role of the helical domain of Gsalpha in the GTPase reaction?
Structural analysis of Gsalpha shows that it is composed of two domains:...
Direct Link | 6th December, 2007
| Department of Medicinal Chemistry and Natural Products, The Lise
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Protein kinase C delta is required for survival of cells expressing activated p21RAS.
Inhibition of protein kinase C (PKC) activity in transformed cells and...
Direct Link | 15th June, 2007
| Cancer Research Center, Boston University School of Medicine, Boston,
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Quantification of oxidative posttranslational modifications of cysteine thiols of p21ras associated with redox modulation of activity using isotope-coded affinity tags and mass spectrometry.
p21ras GTPase is the protein product of the most commonly mutated human...
Direct Link | 26th May, 2007
| Vascular Biology Unit, Boston University School of Medicine, Boston, MA
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The p85 regulatory subunit of PI3K mediates TSH-cAMP-PKA growth and survival signals.
Phosphatidylinositol 3-kinase (PI3K) is necessary for thyroid stimulating...
Direct Link | 24th May, 2007
| Dipartimento di Patologia Molecolare IRCCS Neuromed, Localita Camerelle,
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| Morphoproteomic expression of H-ras (p21ras) correlates with serum monoclonal immunoglobulin reduction in multiple myeloma patients following pamidronate treatment.
| 28th April, 2007
| Division of Laboratory Medicine, Department of Adult Hematology &
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Detailed map of oxidative post-translational modifications of human p21ras using Fourier transform mass spectrometry.
P21ras, the translation product of the most commonly mutated oncogene, is...
Direct Link | 19th April, 2007
| Mass Spectrometry Resource, Department of Biochemistry, Cardiovascular
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Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages.
We recently discovered a novel signaling phenomenon involving a rapid and...
Direct Link | 18th April, 2007
| Department of Pathology and Research Center for Alcoholic Liver and
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| Protein networking in bladder cancer: immunoreactivity for FGFR3, EGFR, ERBB2, KAI1, PTEN, and RAS in normal and malignant urothelium.
| 23rd March, 2007
| The Urological Research Institute, Oslo Urological University Clinic, Aker
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| Adenomatoid hyperplasia of pancreas presenting as tumor.
| 21st March, 2007
| 2nd Department of Propaedeutic Surgery, Athens University Medical School
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Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
Individuals with neurofibromatosis type 1 (NF1) have a high incidence of...
Direct Link | 19th December, 2006
| Department of Pediatrics, Herman B. Wells Center for Pediatric Research,
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S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein.
OBJECTIVE: To understand the mechanism by which oxidants are linked to...
Direct Link | 14th November, 2006
| Director, Vascular Biology Unit, 650 Albany Street, X704, Boston, MA
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Nitric oxide induces thioredoxin-1 nuclear translocation: possible association with the p21Ras survival pathway.
One of the major redox-regulating molecules with thiol reducing activity...
Direct Link | 20th October, 2006
| Departamento de Bioquimica/Biologia Molecular-CINTERGEN Universidade
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Involvement of protein kinase C alpha (PKC alpha) in the early action of angiotensin II type 2 (AT2) effects on neurite outgrowth in NG108-15 cells: AT2-receptor inhibits PKC alpha and p21ras activity.
The aim of the present study was to investigate whether protein kinase C...
Direct Link | 22nd September, 2006
| Service of Endocrinology, Faculty of Medicine, Universite de Sherbrooke,
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