Monday November 23 2009 | Biotechnology feed | All feeds
|
|
|
OsteoarthritisOsteoarthritis , is a condition in which low-grade inflammation results in pain in the joints, caused by abnormal wearing of the cartilage that covers and acts as a cushion inside joints and destruction or decrease of synovial fluid that lubricates those joints. As the bone surfaces become less well protected by cartilage, the patient experiences pain upon weight bearing, including walking and standing. Due to decreased movement because of the pain, regional muscles may atrophy, and ligaments may become more lax. OA is the most common form of arthritis. The word is derived from the Greek word "osteo", meaning "of the bone", "arthro", meaning "joint", and "itis", meaning inflammation, although many sufferers have little or no inflammation. Keeping this in mind, other closely related pathologies include pseudo-arthrosis. This is derived from the Greek words pseudo, meaning "false", and arthrosis, meaning "joint." Radiographic diagnosis results in diagnosis of a fracture within a joint, which is not to be confused with osteoarthritis which is a degenerative pathology affecting a high incidence of distal phalangeal joints of female patients. Many people erroneously think that OA is due to wear and tear. This common misconception is due to the fact that OA typically does not present in younger people. Abnormal loading of joints due to poor posture may increase risk for OA, but only because of the abnormal loading of the joint. If a joint is loaded normally, there should be no OA - the coefficient of friction of a normal joint is frequently described as sliding ice on ice - it will go forever. OA affects nearly 21 million people in the United States, accounting for 25% of visits to primary care physicians, and half of all NSAID prescriptions. It is estimated that 80% of the population will have radiographic evidence of OA by age 65, although only 60% of those will be symptomatic. Treatment is with NSAIDs, local injections of glucocorticoid or hyaluronan, and in severe cases, with joint replacement surgery. There has been no cure for OA, as cartilage has not been induced to regenerate. However, if OA is caused by cartilage damage Autologous Chondrocyte Implantation may be a possible treatment. Clinical trials employing tissue-engineering methods have demonstrated regeneration of cartilage in damaged knees, including those that had progressed to osteoarthritis. Further, in January 2007, Johns Hopkins University was offering to license a technology of this kind, listing several clinical competitors in its market analysis. (From the Wikpedia article Osteoarthritis.) Download PDF containing detailed information. Image ResultsLoading...
BioPortfolio Ltd. offers e-mail and postal lists for Osteoarthritis scientists - we have details of around 3404 individuals working on Osteoarthritis . This page has been viewed 528 times Recent Search Terms used to find this page: osteoarthritis european companies | the discovery of osteoarthritis | osteoarthritis companies | osteoarthritis companies | vimovo and competitors | osteoarthritis research companies | companies developing diagnostics for osteoarthritis | osteoarthritis biotechnical companies | cannabinoids company Osteoarthritis | . Browse BioPortfolio's InDepth service - alphabetically: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z or by Most Publications, recently searched for, or most viewed. Search for Osteoarthritis across BioPortfolio, or for Osteoarthritis Research Reports Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Nothing in this website should be used in
place of personal medical advice from your own qualified medical
practitioner. |
All rights reserved. All other trademarks recognized. |
|
