Osteolysis

Osteolysis refers to an active resorption or dissolution of bone tissue as part of an ongoing disease process.While bone resorption is commonly associated with many diseases or joint problems, the term osteolysis generally refers to a problem common to artificial joint replacements such as total hip replacements, total knee replacements and total shoulder replacements.In total hip replacement, the particles worn off the gliding surface of the ball and socket joint often cause osteolysis. As the body attempts to clean up these loose particles of plastic or metal, the bone grows away from the implant, causing it to loosen. This may require a revision surgery .Distal clavicular osteolysis is often associated with problems weightlifters have with their acromioclavicular joints due to high stresses put on that the clavicle as it meets with the acromion. A common surgery to cure this problem is re-sectioning of the distal clavicle, removing a few millimeters of bone from the very end of the the bone.Category:GeriatricsCategory:OrthopedicsCategory:Musculoskeletal disordersCategory:Arthritisde:Osteolyse Osteoma An osteoma is a new piece of bone usually growing on another piece of bone, typically the skull. It is a benign tumor.When the bone tumor grows on other bone it is known as "homoplastic osteoma"; when it grows on other tissue it is called "heteroplastic osteoma". (From the Wikpedia article Osteolysis.)

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Recent Publications on Osteolysis:
Long-term results of the ABG-1 hydroxyapatite coated total hip arthroplasty: Analysis of 111 cases with a minimum follow-up of 10 years. INTRODUCTION: Medium-term studies of ABG-1 cementless total hip...	21st November, 2009	Department of Orthopaedics and Traumatology, Caremeau Teaching Hospital	Orthop Traumatol Surg Res. 2009 Nov 16. DOI Direct Link
Zoledronic acid protects against osteosarcoma-induced bone destruction but lacks efficacy against pulmonary metastases in a syngeneic rat model. Osteosarcoma (OS) is the most common primary malignant tumour of bone in...	20th November, 2009	Discipline of Orthopaedics and Trauma, University of Adelaide, The Royal	Int J Cancer. 2009 Nov 18. DOI Direct Link
Therapeutic Potential of Adult Bone Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer Bone Metastasis. PURPOSE: Current evidence indicates that an osteoblast lesion in prostate...	19th November, 2009	Authors' Affiliations: Departments of Pathology and Biomedical	Clin Cancer Res. 2009 Nov 17. DOI Direct Link
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Runx2, a bone-specific transcriptional regulator, is abnormally expressed...	17th November, 2009	[1] The Cancer Center Prostate Cancer Discovery and Development Program,	Oncogene. 2009 Nov 16. DOI Direct Link
[Fracture of tibial stem in revision total knee arthroplasty.] An unusual case of implant failure after revision total knee arthroplasty...	17th November, 2009	Ortopedicka klinika LF UP a FN Olomouc.	Acta Chir Orthop Traumatol Cech. 2009 Oct;76(5):428-34.
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Osteolysis Patents:
US Patent No.	Title
7494979	Method for treating congestive heart failure and other disorders
7534246	Ankle replacement system
7534914	Substituted methyl aryl or heteroaryl amide compounds
7550209	Diffusion-hardened medical implant
7550461	Benzofuran and benzothiophene compounds useful in treating cytokine mediated diseases
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