Pancytopenia

Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets. Pancytopenia is generally due to diseases affecting the bone marrow, although peripheral destruction of all lines of blood cells in hypersplenism is a recognised cause. Bone marrow problems causing pancytopenia include myelofibrosis, leukemia, aplastic anemia, and the malignant form of osteoporosis.Chemotherapy for malignancies may also cause pancytopenia, if the drug or drugs used cause bone marrow suppression. Increasingly, HIV is itself a cause for pancytopenia.Rarely, drugs can cause pancytopenia.Pancytopenia usually requires a bone marrow biopsy in order to distinguish among different causes. (From the Wikpedia article Pancytopenia.)

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Recent Publications on Pancytopenia:
[Immune-Mediated Hemolytic Anemia under Oxaliplatin.] The induction of autoimmune hemolysis is a rare side effect of...	12th July, 2008	Second Department of Medicine, Bogenhausen Academic Teaching Hospital,	Z Gastroenterol. 2008 Jul;46(7):695-9. DOI Direct Link
Contribution of regulatory T cells and effector T cell deletion in tolerance induction by costimulation blockadel. Blocking of costimulatory signals for T cell activation leads to tolerance...	9th July, 2008	Division of Clinical Immunology.	J Immunol. 2008 Jul 15;181(2):1034-42.
Postrenal transplant hemophagocytic lymphohistiocytosis and thrombotic microangiopathy associated with parvovirus b19 infection. Persistent anemia is a known consequence of Parvovirus B19 (B19) infection...	4th July, 2008	Department of Nephrology, Tabriz University of Medical Sciences, Tabriz,	Am J Transplant. 2008 Jun;8(6):1340-4. DOI Direct Link
An infant with fever, hepatosplenomegaly, and pancytopenia. There is an increased risk of developing bone marrow depression and...	4th July, 2008	Division of Infectious Diseases, Children's Hospital of Michigan, Wayne	Pediatr Infect Dis J. 2008 Jun;27(6):571. DOI Direct Link
Acute monoblastic leukemia with t(10;11)(p12;q23) presenting with pulmonary involvement: a case report and literature review. A forty-three-year-old Thai man presented with acute fever and dyspnea for...	18th June, 2008	Department of Medicine, Faculty of Medicine, Srinakharinwirot University,	J Med Assoc Thai. 2008 Apr;91(4):559-63.
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BioNews Results for Pancytopenia:
HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted	Twin Cities Business Journal:  Jun 13 2008 11:16AM Matching: pancytopenia
HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted	PR Newswire via Yahoo!:  Jun 13 2008 6:47AM Matching: pancytopenia
HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted	Forbes.com:  Jun 13 2008 6:33AM Matching: pancytopenia
HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted	Calibre Macro World:  Jun 13 2008 6:03AM Matching: pancytopenia
ADVENTRX Presents CoFactor Data At The 2008 Annual Meeting Of The American Society Of Clinical Oncology (ASCO)	Medical News Today:  Jun 4 2008 1:13PM Matching: pancytopenia
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Pancytopenia Clinical Trials:
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia	Diamond Blackfan Anemia
Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia	Anemia, Aplastic;   Red-Cell Aplasia, Pure;   Anemia, Diamond-Blackfan
Collection of Biological Samples From Patients With Hepatitis-Associated Aplastic Anemia	Aplastic Anemia
Risk Factors for the Leakage of Anticancer Drugs to Systemic Circulation by Transcatheter Arterial Chemoembolization	Hepatocellular Carcinoma
Profonycia - Honey for Improving Quality of Patient's Life Receiving Chemotherapy	Myelosuppression Intervention: Dietary Supplement: Profonycia
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Pancytopenia Patents:
US Patent No.	Title
7252994	Human DR4 antibodies and uses thereof
7294331	Methods of using flt3-ligand in hematopoietic cell transplantation
7297511	Interferon alpha: remodeling and glycoconjugation of interferon alpha
7300926	Steroidal quinols and their use for estrogen replacement therapy
7303769	Method for purifying pluri-differentiated mesenchymal progenitor cells
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