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Pharmacogenetics

The terms pharmacogenomics and pharmacogenetics tend to be used interchangeably, and a precise, consensus definition of either remains elusive. Pharmacogenetics is generally regarded as the study or clinical testing of genetic variation that gives rise to differing response to drugs, while pharmacogenomics is the broader application of genomic technologies to new drug discovery and further characterization of older drugs. Pharmacogenetics considers one or at most a few genes of interest, while pharmacogenomics considers the entire genome. (From the Wikpedia article Pharmacogenetics.)

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Recent Publications on Pharmacogenetics:

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Pharmacogenetics of antimalarial drugs: effect on metabolism and transport.
The prevention and management of malaria is primarily based on the use of...
21st November, 2009
Pharmacogenetics, Dr Margarete Fischer-Bosch Institute of Clinical Lancet Infect Dis. 2009 Dec;9(12):760-774.
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Genetic Mapping of Pharmacogenetic Regulatory Variation.
The availability of high-throughput genotyping and sequencing platforms...
21st November, 2009
Channing Laboratory, Division of Pulmonary and Critical Care Medicine, Curr Pharm Des. 2009;15(32):3773-3781.
Genome-Wide Association Studies of Family Data in Pharmacogenetics: A Case Study.
Genome-wide associations studies (GWAS) have become routine in human...
21st November, 2009
Channing Laboratory, Brigham and Women's Hospital and Harvard Medical Curr Pharm Des. 2009;15(32):3764-3772.
Pipeline Pharmacogenetics: A Novel Approach to Integrating Pharmaco-genetics into Drug Development.
There has been a decline in the number of new drugs registered over the...
21st November, 2009
Cabernet Pharmaceuticals, One Science Drive, Box 90344, Durham NC 27708. Curr Pharm Des. 2009;15(32):3754-3763.
Pharmacogenetics of Asthma Therapy.
Asthma is a chronic disorder causing inflammation and reversible airway...
21st November, 2009
Channing Laboratory, Brigham and Women's Hospital and Harvard Medical Curr Pharm Des. 2009;15(32):3742-3753.

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Press Releases About Pharmacogenetics:

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London Genetics Focuses on Partnering Following Successful Pharmacogenetics Conference 30th October, 2009
LONDON, October 30 /PRNewswire/ -- London Genetics Limited, an expert in the use of pharmacogenetics in clinical drug discovery and development, has entered an intensive partnering programme following
Reportlinker Adds Molecular Diagnostics: A Dynamic and Rapidly Broadening Market 29th October, 2009 Reportlinker
-- Major trends in the molecular diagnostics market, such as the increasing number of tests that are commercially available Chapter 1 BACKGROUND AND SCOPE 1.1. Background 1.2. Focus
Reportlinker Adds Pharmacogenomics: Delivering on the Promise 26th October, 2009 Reportlinker
-- Survey results and expert views on utilization of PGx Pharmacogenomics: Delivering on the Promise explores the pharmacogenomic (PGx) realm of personalized medicine, analyzing current R&
Reportlinker Adds Pharmacodiagnostics and Personalized Medicine 2009 (Markets, Challenges, Forecasts and Key Players) Report 24th September, 2009 Reportlinker
-- Current Market Size for U.S. Pharmacodiagnostics -- Forecasted Likely and 'Best Case' Revenue Projections to 2018. -- An Overview of the Concept, Past Successes
Inherited Risk Factors Increase Odds of Developing Childhood Acute Lymphoblastic Leukemia 16th August, 2009 St. Jude Children's Research Hospital
St. Jude Children's Research Hospital scientists lead survey of genome that identifies new genes linked to cancer risk and treatment response MEMPHIS, Tenn., Aug. 16 /PRNewswire-USNewswire/ --

BioNews Results for Pharmacogenetics:

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Imaging, Genetics on Verge of Transforming Psychiatry [Association News]
Psychiatric News:  Nov 20 2009 7:09PM Matching: pharmacogenetics
[Review] Pharmacogenetics of antimalarial drugs: effect on metabolism and transport
Lancet Infectious Diseases:  Nov 16 2009 5:53PM Matching: pharmacogenetics
Developmental Pharmacogenetics: A General Paradigm for Application to Neonatal Pharmacology and Toxicology
Clinical Pharmacology & Therapeutics:  Nov 16 2009 12:20PM Matching: pharmacogenetics
Population Pharmacokinetics and Pharmacogenetics of Tacrolimus in De Novo Pediatric Kidney Transplant Recipients
Clinical Pharmacology & Therapeutics:  Nov 16 2009 12:20PM Matching: pharmacogenetics
Cytokinetics Announces Non-Clinical Data Relating to GSK-923295 to Be Presented at the 2009 AACR-NCI-EORTC Int
Pharmacy Choice:  Nov 13 2009 6:26AM Matching: pharmacogenetics
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Pharmacogenetics Patents:

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US Patent No.Title
7529718 Fast computer data segmenting techniques
7553616 Methods for drug discovery, disease treatment, and diagnosis using metabolomics
7553826 Cytarabine monophosphate prodrugs
7553939 T cell regulatory genes and methods of use thereof
7556923 Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders

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Companies working in the area of Pharmacogenetics from Bioportfolio's Biocorporate database :

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Gene Quest Incorporated

Gene Quest provides laboratory services, including pharmacogenetics, to facilitate the drug development process. The innovative platform technology is Immobilized Sample Amplification (ISA) with a...
www.gene-quest.com/        View full profile
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Interleukin Genetics

Interleukin Genetics aims to be the world leader in understanding the genetics of inflammation, one of the body's most important defense mechanisms. Our scientists and clinicians study how common...
www.ilgenetics.com/        View full profile
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Solexa Limited

Solexa is developing a breakthrough technology for DNA sequencing. Its Single Molecule Arrays (SMAs) promise the powerful combination of massively parallel sequencing with amplification-free ‘one pot’...
www.solexa.co.uk/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Pharmacogenetics scientists - we have details of around 619 individuals working on Pharmacogenetics .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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