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Polymyositis

Polymyositis is a type of inflammatory myopathy, related to dermatomyositis and inclusion body myositis. Polymyositis means 'many muscle inflammation'. Polymyositis tends to become evident in adulthood, presenting with bilateral proximal muscle weakness, often noted in the upper legs due to early fatigue while walking. Sometimes the weakness presents itself by the person being unable to rise from a seated position without help, or inability to raise their arms above their head. The weakness is generally progressive, accompanied by lymphocytic inflammation . The cause is unknown, but seems to be related to autoimmune factors, genetics, and perhaps viruses. In rare cases, the cause is known to be infectious, associated with the pathogens that cause Lyme disease, toxoplasmosis, and others.Polymyositis, like dermatomyositis, strikes females with greater frequency than males. The skin involvement of dermatomyositis is absent in polymyositis. (From the Wikpedia article Polymyositis.)

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Recent Publications on Polymyositis:

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Malignancy Is Associated with Dermatomyositis But Not Polymyositis in Northern New England, USA.
OBJECTIVE: To retrospectively evaluate the association of idiopathic...
18th November, 2009
From the Department of Rheumatology, Dartmouth-Hitchcock Medical Center , J Rheumatol. 2009 Nov 16.
DOI Direct Link
Polymyositis presenting with cardiac manifestations: Report of two cases and review of the literature.
We report two patients with severe cardiac manifestations at the time of...
17th November, 2009
Department of Neurology, The University of Alabama at Birmingham, Clin Neurol Neurosurg. 2009 Nov 10.
DOI Direct Link
The geoepidemiology of autoimmune muscle disease.
Dermatomyositis (DM), polymyositis (PM), and sporadic inclusion-body...
13th November, 2009
Muscle Research Unit. Service of Internal Medicine, Institut Clinic de Autoimmun Rev. 2009 Nov 10.
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Epstein-Barr virus (EBV) associated lymphoepithelioma-like thymic carcinoma associated with paraneoplastic syndrome of polymyositis: a rare tumor with rare association.
Thymic carcinomas are rare neoplasms representing less than 1% of all...
7th November, 2009
Department of Nuclear Medicine, University of Washington School of Clin Nucl Med. 2009 Oct;34(10):686-8.
DOI Direct Link
Review article: gastrointestinal complications of myositis.
Abstract Background: The inflammatory myopathies are a group of acquired...
6th November, 2009
Department of Medicine UMDNJ-Robert Wood Johnson Medical School New Aliment Pharmacol Ther. 2009 Nov 3.
DOI Direct Link

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BioNews Results for Polymyositis:

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Medical News: MedImmune Highlights Inflammatory Disease Portfolio At 73rd Annual Meeting Of The American College Of Rheumatology
Medical News Today:  Oct 16 2009 1:11PM Matching: polymyositis
MedImmune Highlights Inflammatory Disease Portfolio at 73rd Annual Meeting of the American College of Rheumato
Freshnews.com:  Oct 15 2009 7:49PM Matching: polymyositis
MedImmune Highlights Inflammatory Disease Portfolio at 73rd Annual Meeting of the American College of Rheumatology
SmartBrief:  Oct 15 2009 7:47PM Matching: polymyositis
MedImmune Highlights Inflammatory Disease Portfolio at 73rd Annual Meeting of the American College of Rheumato
Pharma Live:  Oct 15 2009 7:36PM Matching: polymyositis
MedImmune Highlights Inflammatory Disease Portfolio at 73rd Annual Meeting of the American College of Rheumato
Cincinnati Business Journal:  Oct 15 2009 7:10PM Matching: polymyositis
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Polymyositis Patents:

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US Patent No.Title
7592349 Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptors
7598243 Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
7598244 [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof
7598247 Immunomodulating heterocyclic compounds
7598248 Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use

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BioPortfolio Ltd. offers e-mail and postal lists for Polymyositis scientists - we have details of around 784 individuals working on Polymyositis .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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