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Radioimmunotherapy

Radio immunotherapy utilizes an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells while decreasing the dose to normal tissues. By its nature, RIT requires a tumor cell to express an antigen that is unique to the neoplasm or is not accessible in normal cells. (From the Wikpedia article Radioimmunotherapy.)

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Recent Publications on Radioimmunotherapy:

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[Guideline for radioimmunotherapy of CD20+ follicular B-cell non-Hodgkin s lymphoma.]
This guideline is a prerequisite for the quality management in the...
11th November, 2009
Prof. Dr. Manfred Fischer, Im Bodden 60, 34125 Kassel, Germany. Nuklearmedizin. 2009 Nov 9;48(6).
DOI Direct Link
Anti-Infective Strategies of the Future: Is there Room for Species-Specific Antibacterial Agents?
Broad-spectrum antibiotics, directed against conserved bacterial targets,...
11th November, 2009
Microbiology Consultant, D-79576 Weil am Rhein, Germany. Curr Pharm Des. 2009 Nov 10.
Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma.
Innovation in the management of brain metastases is needed. We evaluated...
6th November, 2009
Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, 1275 J Neurooncol. 2009 Nov 5.
DOI Direct Link
Good things come in small packages: low-dose radiation as palliation for indolent non-Hodgkin lymphomas.
Numerous management options are available to patients with advanced-stage...
4th November, 2009
Harvard Radiation Oncology Program, Brigham and Women's Leuk Lymphoma. 2009 Nov;50(11):1765-72.
Localization of radiolabeled anti-CEA antibody in subcutaneous and intrahepatic colorectal xenografts: influence of tumor size and location within host organ on antibody uptake.
INTRODUCTION: Radioimmunotherapy (RIT) has been shown to be more effective...
31st October, 2009
Cancer Research UK Targeting and Imaging Group, Research Department of Nucl Med Biol. 2009 Nov;36(8):883-94. Epub 2009 Oct 3.
DOI Direct Link

View more research publications.

Press Releases About Radioimmunotherapy:

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Reportlinker Adds World Market for Cancer Therapeutics and Biotherapeutics, 3rd. Edition, The Report 24th September, 2009 Reportlinker
-- SERMS The report includes market share by type of cancer and market share by company for each of the three major segments. It also includes statistical information for cancers by type
Zevalin Data to be Presented at ASH 2008 4th December, 2008 Cell Therapeutics, Inc.
SEATTLE, Dec. 4 /PRNewswire-FirstCall/ -- Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) today announced presentations or posters of interest related to Zevalin(R) (ibritumomab tiuxetan) to

BioNews Results for Radioimmunotherapy:

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Spectrum Pharma: Zevalin Has Blockbuster Potential
Seeking Alpha:  Oct 25 2009 1:51PM Matching: radioimmunotherapy
Manchester scientists take on cancer with pioneering radiotherapy treatment
Cancer Research UK:  Oct 14 2009 2:27AM Matching: radioimmunotherapy
Manchester scientists test radioimmunotherapy in early phase clinical trials
News-Medical.Net:  Oct 9 2009 9:26AM Matching: radioimmunotherapy
Manchester scientists test radioimmunotherapy in early phase clinical trials
News-Medical.Net:  Oct 9 2009 9:26AM Matching: radioimmunotherapy

Radioimmunotherapy Clinical Trials:

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BEAM+131I-Anti-B1 & Autologous Hematopoietic Stem Cell Transplant for Recurrent Non-Hodgkin's Lymphoma

Radioimmunotherapy Patents:

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US Patent No.Title
7550427 Poly-pegylated protease inhibitors
7574251 Method and system for adapting a radiation therapy treatment plan based on a biological model
7576066 Nucleic acid compositions for stimulating immune responses
7579187 Anti-A33 antibody
7582281 Ethylenedicysteine (EC)-drug conjugates compositions and methods for tissue specific disease imaging

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Companies working in the area of Radioimmunotherapy from Bioportfolio's Biocorporate database :

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Company Name

Center of Molecular Immunology

The Center of Molecular Immunology (CIM) is a Cuban Biotechnological Institution devoted to basic research, product development and production of mammalian cell culture products such as monoclonal...
www.cim.sld.cu/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Radioimmunotherapy scientists - we have details of around 267 individuals working on Radioimmunotherapy .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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