Recent Publications on Radioligand Assay: |  |
Synthesis and receptor binding of new thieno[2,3-d]-pyrimidines as selective ligands of 5-HT(3) receptors.
With the aim to develop new potent and selective ligands of 5-HT(3)-type...
Direct Link | 6th September, 2008
| Dipartimento di Scienze Farmaceutiche, Universita di Catania, Catania,
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1-[(Imidazolidin-2-yl)imino]indazole. Highly alpha 2/I1 selective agonist: synthesis, X-ray structure, and biological activity.
Novel benzazole derivatives bearing a (imidazolidin-2-yl)imino moiety at...
Direct Link | 6th September, 2008
| Department of Chemical Technology of Drugs and Department of
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Conformationally constrained analogues of N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716): design, synthesis, computational analysis, and biological evaluations.
Structure-activity relationships (SARs) of 1 (SR141716) have been...
Direct Link | 6th September, 2008
| Chemistry and Life Sciences, Research Triangle Institute, Research
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Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide.
We demonstrate here that covalent dimerization of 5-HT 1 ligands is an...
Direct Link | 6th September, 2008
| Department of Medicinal Chemistry, Theravance, Inc., 901 Gateway
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| [Use of ABC typing to redefine subtypes of acute-onset type 1 diabetes mellitus: study of 308 patients]
| 2nd September, 2008
| Diabetes Center, Institute of Metabolism and Endocrinology, Second Xiangya
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| [Diagnostic value of protein tyrosine phosphatase-2beta antibody (IA-2betaA) in type 1 diabetes]
| 2nd September, 2008
| Diabetic Center, Institute of Metabolism and Endocrinology, Second Xiangya
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Glucagon-like peptide 1-receptor scans to localize occult insulinomas.
OBJECTIVE: Detection of antibodies to ribonucleoproteins represents a...
Direct Link | 30th August, 2008
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Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor.
BACKGROUND: Palonosetron is a 5-HT(3)-receptor antagonist (5-HT(3)-RA)...
Direct Link | 30th August, 2008
| Research and Translational Development, MGI PHARMA INC, 6611 Tributary
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Quantitative assessment of antibodies to ribonucleoproteins in primary Sjogren's syndrome : correlation with B cell biomarkers and disease activity.
OBJECTIVE: Detection of antibodies to ribonucleoproteins represents a...
Direct Link | 21st August, 2008
| Immunology, Necker Hospital, Paris, France.
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Gamma-aminobutyric acid A receptor functional decrease in the hypothalamus during pancreatic regeneration in rats.
OBJECTIVE: In the present study, we investigated the alteration of...
Direct Link | 21st August, 2008
| Department of Biotechnology, Molecular Neurobiology and Cell Biology Unit,
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Novel steroid receptor phyto-modulator compound a inhibits growth and survival of prostate cancer cells.
Androgen receptor (AR)- and glucocorticoid receptor (GR)- mediated...
Direct Link | 19th August, 2008
| Department of Dermatology, Northwestern University, Chicago, Illinois,
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Age-related changes in endothelin-1 receptor subtypes in rat heart.
Density, affinity, and subtype distribution of endothelin-1 (ET-1) binding...
Direct Link | 8th August, 2008
| CNR Institute of Clinical Physiology, Laboratory of Cardiovascular
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| Selective inhibition of cyclooxygenase-2 suppresses the growth of pancreatic cancer cells in vitro and in vivo.
| 31st July, 2008
| Department of Gastroenterology, Tenth Hospital, Tongji University,
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Measurement of phosphoinositide 3-kinase and its products to study adipogenic signal transduction.
Adipogenesis is an important component of adipose tissue development and...
Direct Link | 30th July, 2008
| Department of Medicine, Microbiology and Immunology, University of Ottawa,
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| Flow cytometry application for studies on adenosine A2A receptors expression.
| 25th June, 2008
| Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy,
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