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Raf KinasesDownload PDF containing detailed information.
Recent Publications on Raf Kinases: |  |
Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation.
Sprouty2 is a feedback regulator that controls the... | 18th November, 2009
| The Beatson Institute for Cancer Research, Glasgow, United Kingdom.
| Cancer Res. 2009 Sep 1;69(17):6773-81. Epub 2009 Aug 18.
DOI Direct Link |
(-)-Epigallocatechin-3-gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt.
The effect of epigallocatechin gallate (EGCG) on cell survival was studied... | 17th November, 2009
| Department of Oral Pathology, Pusan National University, Yang San, South
| Am J Chin Med. 2009;37(4):723-34.
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Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation.
BAD is a proapoptotic member of the Bcl-2 protein family that is regulated... | 11th November, 2009
| Institute for Medical Radiation and Cell Research, University of
| J Biol Chem. 2009 Oct 9;284(41):28004-20. Epub 2009 Aug 10.
DOI Direct Link |
Can BAD pores be good? New insights from examining BAD as a target of RAF kinases.
The objective of this study was chromosomal analysis and measurement of... | 10th November, 2009
| Max-Planck-Institut fur Herz- und Lungenforschung, W.G.
| Adv Enzyme Regul. 2009 Nov 4.
DOI Direct Link |
RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways.
MAPkinase signalling is essential for cell growth, differentiation and... | 3rd November, 2009
| Department of Pharmacology, Emory University School of Medicine, Atlanta,
| Cell Signal. 2009 Oct 27.
DOI Direct Link |
→View more research publications. |
Press Releases About Raf Kinases:
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| Bayer and Onyx Announce Nexavar Data Presentations at 60th American Association for the Study of Liver Diseases Annual Meeting |
29th October, 2009 |
Onyx Pharmaceuticals, Inc. |
-- Late Breaker #9
First-in-men Demonstration of Sorafenib Plus TACE for the Treatment of Advanced Hepatocellular Carcinoma (SOCRATES trial)
-- Dr. Andreas Erhardt, Klinik fur
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| Bayer and Onyx Initiate Phase 3 Trial of Nexavar in Patients With Non-Responsive Thyroid Cancer |
23rd October, 2009 |
Onyx Pharmaceuticals, Inc. |
WAYNE, N.J. and EMERYVILLE, Calif., Oct. 23 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced the companies have begun
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| Results Reported for Exploratory Phase 2 Study of Nexavar in Combination With Chemotherapeutic Agent Paclitaxel for Treatment of Advanced Breast Cancer |
30th September, 2009 |
Onyx Pharmaceuticals, Inc. |
WAYNE, N.J. and EMERYVILLE, Calif., Sept. 30 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced results from a randomized, placebo
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| Sunesis Reports Financial Results for the Second Quarter 2009 |
29th July, 2009 |
Sunesis Pharmaceuticals, Inc. |
-- On July 24, 2009, Sunesis applied to transfer the listing of its common
stock from The NASDAQ Global Market to The NASDAQ Capital Market. The
NASDAQ Capital Market is a
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| Debiopharm Group and Moffitt Cancer Center Sign Development and Commercialisation Agreement for Small Molecule Debio 0928 in Early Preclinical Development for Treatment of Solid Tumours |
18th June, 2009 |
Debiopharm Group |
LAUSANNE, Switzerland and TAMPA, Florida, June 18 /PRNewswire/ --
Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group
of companies with a focus on the development of
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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
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