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Ras Proteins

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Recent Publications on Ras Proteins:

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C. elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis.
RNA regulators are critical for animal development, especially in the germ...
11th July, 2008
Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, RNA. 2008 Jul;14(7):1378-89. Epub 2008 May 30.
DOI Direct Link
Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila.
The proto-oncoprotein Raf is pivotal for mitogen-activated protein kinase...
11th July, 2008
Department of Biomedical Genetics, University of Rochester Medical Center, PLoS Biol. 2008 May 20;6(5):e128.
DOI Direct Link
How is SOS activated? Let us count the ways.
Farnesyltransferase (FTase) is a zinc enzyme that has been the subject of...
9th July, 2008
Nat Struct Mol Biol. 2008 Jun;15(6):538-40.
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An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway.
The growth and metabolic actions of growth hormone (GH) are believed to be...
9th July, 2008
Institute for Molecular Bioscience and School of Biomedical Sciences, Nat Cell Biol. 2008 Jun;10(6):740-7. Epub 2008 May 18.
DOI Direct Link
A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts.
Point mutations in three kinds of Ras protein (H-, K-, and N-Ras) that...
8th July, 2008
Department of Biochemistry, Yonsei University, Seoul, Korea. Proteomics. 2008 Jul 7;.
DOI Direct Link

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Ras Proteins Clinical Trials:

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Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome
Leukemia;   Myelodysplastic Syndromes
Safety and Efficacy of the Therapeutic Vaccine GI-4000 in Combination With Gemcitabine Versus Placebo for the Treatment of Non-Metastatic, Post-Resection Pancreas Cancer
Pancreas Cancer

Ras Proteins Patents:

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US Patent No.Title
7186513 Methods for monitoring multiple gene expression
7250263 Methods and compositions for identifying receptor effectors
7250496 Bioinformatically detectable group of novel regulatory genes and uses thereof
7253183 Method of use of (imidazol-5-yl)methyl-2-quinolinone derivatives to inhibit smooth muscle cell proliferation
7253184 4-Substituted quinolines as antitumor agents

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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