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Retinoblastoma

Retinoblastoma is a cancer of the retina. Development of this tumor is initiated by mutations that inactivate both copies of the RB1 gene, which codes for the retinoblastoma protein. (From the Wikpedia article Retinoblastoma.)

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Recent Publications on Retinoblastoma:

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Retinoblastoma Family Proteins Have Distinct Functions in Pulmonary Epithelial Cells In vivo Critical for Suppressing Cell Growth and Tumorigenesis.
Lung cancer is the leading cause of cancer deaths, accounting for more...
6th November, 2009
Pathology and Laboratory Medicine and Pulmonary Biology, Cincinnati Cancer Res. 2009 Nov 3.
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Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.
The retinoblastoma (RB) tumor suppressor pathway is disrupted at high...
6th November, 2009
Thomas Jefferson University, United States; J Biol Chem. 2009 Nov 2.
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Radiation-induced spindle cell sarcoma: a rare case report.
Ionizing radiation has been known to induce malignant transformation in...
4th November, 2009
Department of Oral Medicine and Radiology, Government Dental College and Indian J Dent Res. 2009 Jul-Sep;20(3):380-4.
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RNAi mediated acute depletion of Retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation.
ABSTRACT: BACKGROUND: Changes in chromosome number or structure as well as...
4th November, 2009
BMC Cell Biol. 2009 Nov 2;10(1):79.
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Pictorial essay: B-scan ultrasonography in ocular abnormalities.
B-scan ultrasonography (USG) is a simple, noninvasive tool for diagnosing...
3rd November, 2009
Department of Radiodiagnosis, Rural Medical College, Loni 413736, Rahata, Indian J Radiol Imaging. 2009 Apr-Jun;19(2):109-15.
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Press Releases About Retinoblastoma:

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Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases 7th August, 2009 Children's Hospital Los Angeles
LOS ANGELES, Aug. 7 /PRNewswire-USNewswire/ -- A new drug delivery system that uses a tiny silicone cup filled with any drug and sealed to the outer surface (episclera) of the eyeball may offer a more
Frost & Sullivan Recognizes Neotropix's Approach to the Treatment of Small Cell Lung Cancer and Neuroendocrine Cancers 13th January, 2009 Frost & Sullivan
Innovative Therapy Ensures Greater Patient Compliance, Improves Quality of Life MOUNTAIN VIEW, Calif., Jan. 13 /PRNewswire/ -- Based on its recent analysis of the biopharmaceuticals market, Frost

BioNews Results for Retinoblastoma:

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Pediatrician recommends red reflex vision test for all newborns
News-Medical.Net:  Nov 7 2009 6:06AM Matching: retinoblastoma
Toddler Battles Rare Eye Cancer
KETV.com:  Nov 5 2009 6:32AM Matching: retinoblastoma
pRb loss predicts good outcome in triple negative breast cancer
MedWire News:  Nov 5 2009 3:42AM Matching: retinoblastoma
Outcomes of cataract surgery following radiation treatment for retinoblastoma
MDLinx:  Nov 3 2009 10:35AM Matching: retinoblastoma
Contrast-Enhancement of the Anterior Eye Segment in Patients with Retinoblastoma: Correlation between Clinical, MR Imaging, and Histopathologic Findings
MDLinx:  Nov 2 2009 1:34PM Matching: retinoblastoma
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Retinoblastoma Clinical Trials:

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Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma

Retinoblastoma Patents:

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US Patent No.Title
7598060 Rapid analysis of variations in a genome
7601700 Modulation of eIF4E expression
7601703 Enzyme catalyzed therapeutic agents
7601719 Compounds, methods and pharmaceutical compositions for inhibiting PARP
7601739 Compounds having antiestrogenic and tissue selective estrogenic properties, and compounds with anti-androgenic properties for treatment of prostate cancer and androgen receptor dependent diseases

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Companies working in the area of Retinoblastoma from Bioportfolio's Biocorporate database :

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Oncogene Research projects

Today, OncogeneScienceŽ based in Cambridge MA (at the original Applied bioTechnology facility) develops, manufactures, and markets high quality, ready-to-use cancer reagent systems to commercial and...
www.oncogene.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Retinoblastoma scientists - we have details of around 1431 individuals working on Retinoblastoma .


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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH. Thumbshots from Thumbshots.org

 

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