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Saccharopine Dehydrogenases

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Recent Publications on Saccharopine Dehydrogenases:

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Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae.
Kinetic studies were carried out for histidine-tagged saccharopine...
11th June, 2008
Department of Chemistry and Biochemistry, UniVersity of Oklahoma, 620 Biochemistry. 2008 May 13;47(19):5417-23. Epub 2008 Apr 17.
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Modifying lysine biosynthesis and catabolism in corn with a single bifunctional expression/silencing transgene cassette.
Although it is one of the major crops in the world, corn has poor...
26th February, 2008
Mystic Research, Monsanto Company, 62 Maritime Drive, Mystic, CT 06355, Plant Biotechnol J. 2008 Jan;6(1):13-21. Epub 2007 Aug 28.
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Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae.
Three structures of saccharopine dehydrogenase (l-lysine-forming) (SDH)...
12th January, 2008
Department of Chemistry and Biochemistry, University of Oklahoma, 620 Biochemistry. 2007 Nov 6;46(44):12512-21. Epub 2007 Oct 16.
DOI Direct Link
Structural studies of the final enzyme in the alpha-aminoadipate pathway-saccharopine dehydrogenase from Saccharomyces cerevisiae.
The 1.64 A structure of the apoenzyme form of saccharopine dehydrogenase...
7th December, 2007
Department of Biochemistry, McGill University, Montreal, Quebec, Canada J Mol Biol. 2007 Oct 26;373(3):745-54. Epub 2007 Aug 24.
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High-lysine corn generated by endosperm-specific suppression of lysine catabolism using RNAi.
Because of the limited lysine content in corn grain, synthetic lysine...
27th October, 2007
Mystic Research, Monsanto Company, 62 Maritime Drive, Mystic, CT 06355, Plant Biotechnol J. 2007 Sep;5(5):605-14. Epub 2007 Jun 6.
DOI Direct Link

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Saccharopine Dehydrogenases Patents:

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US Patent No.Title
7071383 Chimeric genes and methods for increasing the lysine and threonine content of the seeds of plants
6459019 Chimeric genes and methods for increasing the lysine and threonine content of the seeds of plants
5773691 Chimeric genes and methods for increasing the lysine and threonine content of the seeds of plants

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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