Sciatica

Sciatica is a set of symptoms including pain that may be caused by general compression and/or irritation of one of five nerve roots that give rise to the sciatic nerve, or by compression or irritation of the sciatic nerve itself. The pain is felt in the lower back, buttock, and/or various parts of the leg and foot. In addition to pain, which is sometimes severe, there may be numbness, muscular weakness, and difficulty in moving or controlling the leg. Typically, the symptoms are only felt on one side of the body.Although sciatica is a relatively common form of low back pain and leg pain, the true meaning of the term often is misunderstood. Sciatica is a set of symptoms rather than a diagnosis for what is irritating the root of the nerve, causing the pain. This point is important, because treatment for sciatica or sciatic symptoms will often be different, depending upon the underlying cause of the symptoms.The first cited use of the word "sciatica" was registered in 1450. (From the Wikpedia article Sciatica.)

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Recent Publications on Sciatica:
Isometric trunk muscle strength and body sway in relation to low back pain in young adults. STUDY DESIGN: A cross-sectional study on young adults. OBJECTIVE: To...	11th July, 2008	Department of Sports Medicine, Deaconess Institute of Oulu, Oulu, Finland.	Spine. 2008 Jun 1;33(13):E435-41. DOI Direct Link
Kinetics of regression of sciatica and pain in the low back after lumbar macrodiscectomy in human immunodeficiency virus carriers. STUDY DESIGN: Prospective longitudinal clinical study. OBJECTIVE: To...	11th July, 2008	Faculty of Medicine and Biomedical Sciences, University of Yaounde I,	Spine. 2008 Jun 1;33(13):E411-3. DOI Direct Link
Thioctic Acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc : a randomized, double-blind, comparative study. BACKGROUND and objective: Sciatica is a painful condition characterized by...	5th July, 2008	Ortopedia Pediatrica, Istituto Ortopedico Gaetano Pini, Milan, Italy.	Clin Drug Investig. 2008;28(8):495-500.
Computerized adaptive testing in back pain: validation of the CAT-5D-QOL. STUDY DESIGN: We have conducted an outcome instrument validation study....	4th July, 2008	Department of Health Care and Epidemiology, University of British	Spine. 2008 May 20;33(12):1384-90. DOI Direct Link
Participation of 5-hydroxytryptamine in pain-related behavior induced by nucleus pulposus applied on the nerve root in rats. STUDY DESIGN: The role of 5-hydroxytryptamine (5-HT) in sciatica in lumbar...	4th July, 2008	Department of Orthopaedic Surgery, Fukushima Medical University School of	Spine. 2008 May 20;33(12):1330-6. DOI Direct Link
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BioNews Results for Sciatica:
Study Finds Keeping A Food Diary Really Works	CBS 4 Denver:  Jul 9 2008 11:29AM Matching: sciatica
TopAbstracts in Back Pain 07/02/2008	Doctors Guide:  Jul 3 2008 4:38PM Matching: sciatica
Alternatives to Ibuprofen For Pain Relief	Peoples Pharmacy:  Jun 6 2008 11:33PM Matching: sciatica
Gabapentin as a Potential Option for Treatment of Sciatica	Medscape:  Jun 5 2008 7:12PM Matching: sciatica
Gabapentin as a Potential Option for Treatment of Sciatica	Pharmacotherapy:  Jun 4 2008 6:31PM Matching: sciatica
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Sciatica Clinical Trials:
The Efficacy of Oral Steroids in the Treatment of Acute Sciatica	Sciatica Intervention: Drug: Oral Prednisone
Efficacy of Intravenous Dexamethasone for Acute Disc Herniation-Induced Sciatica	RADICULAR PAIN
Effect of Antidepressants on Back Pain	Back Pain;   Sciatica
A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol(CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain	Osteoarthritis;   Sciatica;   Pain Assessment;   Arthralgia
Dalteparin vs Unfractionated Heparin For The Prevention Of Venous Thromboembolism (VTE) In Hospitalized Acutely Ill Medical Patients	Respiratory Insufficiency;   Infection;   Inflammatory Bowel Diseases;   Heart Failure, Congestive;   Sciatica
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Sciatica Patents:
US Patent No.	Title
7288564	Indole derivatives
7329659	Substituted-1-phthalazinamines as vr-1 antagonists
7329667	CRF receptor antagonists
7331956	Methods and apparatus for treating back pain
7337005	Methods for stimulating a nerve root ganglion
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