Spondylitis

:Not to be confused with spondylosis.Spondylitis is an inflammation of a vertebra. Any disorder of the spinal column may be called spondylopathy, also. What is spondylitis?Spondylitis is the name given to a group of chronic or long lasting diseases also called Spondyloarthritis or Spondyloarthropathy . These diseases are forms of inflammatory arthritis that primarily affect the spine, although other joints and organs can become involved. The group of diseases in the spondylitis family includes: Ankylosing spondylitis - Ankylosing spondylitis is the primary disease in the spondylitis family of diseases and is a form of chronic autoimmune arthritis that primarily affects the spine and sacroiliac joints, although other joints can become involved. Occurring primarily in young adults, , AS causes inflammation of the spinal joints that can lead to severe, chronic pain and discomfort.Undifferentiated spondyloarthropathy - Undifferentiated Spondyloarthropathy is a term used to describe symptoms and signs of spondylitis in someone who does not meet the criteria for a definitive diagnosis of AS or related disease. Over time, some people with USpA will develop a well-defined form of spondylitis such as ankylosing spondylitis.Juvenile spondyloarthropathy - Juvenile-onset spondyloarthritis , also known as Juvenile Spondyloarthropathy, is the medical term for a group of childhood rheumatic diseases, which cause arthritis before the age of 16 and may span through adult life. JSpA typically causes pain and inflammation in the joints in the lower part of the body, for example, the pelvis, hips, knees and ankles.Psoriatic arthritis - In 5-10% of those with psoriasis, arthritis also appears. In most cases, the psoriasis will precede the arthritis, sometimes by many years. When arthritis symptoms occur with psoriasis, it is called psoriatic arthritis .Reactive arthritis - Reactive Arthritis is a form of arthritis that can cause inflammation and pain in the joints, the skin, the eyes, the bladder, the genitals and the mucus membranes. Reactive arthritis is thought to occur as a "reaction" to an infection that started elsewhere in the body, generally in the genitourinary or gastrointestinal tract.Enteropathic arthritis - Enteropathic arthritis is a form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease , the two best-known types of which are ulcerative colitis and Crohn's disease. The most common areas affected by enteropathic arthritis are inflammation of the peripheral joints, as well as the abdominal pain and possibly bloody diarrhea associated with the IBD component of the disease.Pott's disease - a form of spondylitis that is the result of extrapulmonary tuberculosis. (From the Wikpedia article Spondylitis.)

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Recent Publications on Spondylitis:
Localized Cutaneous Leishmaniasis due to Leishmaniainfantum in a Patient Treated with Infliximab. We report the first case of cutaneous leishmaniasis in a patient treated...	13th November, 2009	Service de Medecine Interne A, Centre Hospitalier Universitaire,	Dermatology. 2009 Nov 12. DOI Direct Link
The use of tumour necrosis factor alpha-blockers in daily routine. An Austrian consensus project. To define relevant disease parameters and their respective limits...	12th November, 2009	Karl Landsteiner-Institute for Clinical Rheumatology, First and Second	Clin Rheumatol. 2009 Nov 11. DOI Direct Link
Percutaneous discectomy-continuous irrigation and drainage for tuberculous lumbar spondylitis: a report of two cases. Percutaneous curettage and continuous irrigation were performed for...	11th November, 2009	Department of Orthopaedic Surgery, Kagawa University School of Medicine,	Case Report Med. 2009;2009:632981. Epub 2009 Nov 8. DOI Direct Link
Bone morphogenetic protein signaling and arthritis. Chronic joint diseases have a major impact on society as patients suffer...	11th November, 2009	Laboratory for Skeletal Development and Joint Disorders, Department of	Cytokine Growth Factor Rev. 2009 Nov 7. DOI Direct Link
Insights into the pathogenesis of axial spondyloarthropathy based on gene expression profiles. ABSTRACT: INTRODUCTION: Axial spondyloarthropathy (SpA) is a group of...	11th November, 2009		Arthritis Res Ther. 2009 Nov 9;11(6):R168. DOI Direct Link
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Press Releases About Spondylitis:
New Data From the PRESTA Trial Demonstrate the Benefit of Enbrel(R) in Patients With Psoriasis and Psoriatic Arthritis	9th October, 2009		MAIDENHEAD, England, October 9 /PRNewswire/ -- Data signalling that Enbrel(R) (etanercept) can improve the quality of life for people with psoriasis and psoriatic arthritis were presented at the 18th
SIMPONI(TM) (golimumab) Receives European Approval as Once-Monthly Subcutaneous Anti-TNF for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis with Novel SmartJect(TM) Autoinjector	6th October, 2009	Schering-Plough Corporation	-- For the treatment of severe, active AS in adult patients who have responded inadequately to conventional therapy. Centocor Ortho Biotech Inc. developed and discovered SIMPONI and
SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis	26th June, 2009	Schering-Plough Corporation	Positive Opinion Recommends Approval of New Anti-TNF Therapy in Three Rheumatic Diseases with Novel SmartJect(TM) Autoinjector HORSHAM, Pa. and KENILWORTH, N.J., June 26 /PRNewswire-FirstCall/ --
SIMPONI(TM) (golimumab) Receives FDA Approval as First Once-Monthly Anti-TNF for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis	24th April, 2009	Centocor Ortho Biotech Inc.	First Subcutaneous Anti-TNF to Launch with Three Rheumatic Indications Simultaneously and with Novel SmartJect(TM) Autoinjector HORSHAM, Pa., April 24 /PRNewswire/ -- Centocor Ortho Biotech Inc.
Health Canada Approves SIMPONI(TM) (golimumab) for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis	13th April, 2009	Centocor Ortho Biotech Inc.	Canadian Approval Is World's First Regulatory Approval for SIMPONI HORSHAM, Pa. and KENILWORTH, N.J., April 13 /PRNewswire-FirstCall/ Centocor Ortho Biotech Inc. and Schering-Plough

BioNews Results for Spondylitis:
Use of a Percutaneous Diskectomy Device to Facilitate the Diagnosis of Infectious Spondylitis	MDLinx:  Nov 13 2009 11:02AM Matching: spondylitis
Rheumatology: Scientists at Korea University, Division of Rheumatology publish new data on rheumatology	NewsRX:  Nov 6 2009 5:30AM Matching: spondylitis
NSAIDS: Recent findings in NSAIDS described by researchers from Pfizer Inc.	NewsRX:  Nov 3 2009 6:50AM Matching: spondylitis
Etanercept Improves Pulmonary Capacity in Patients With Advanced Ankylosing Spondylitis	Abstracts in Hematology and Oncology:  Oct 21 2009 7:56PM Matching: spondylitis
Etanercept Improves Pulmonary Capacity in Patients With Advanced Ankylosing Spondylitis	Medscape:  Oct 21 2009 7:21PM Matching: spondylitis
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Spondylitis Clinical Trials:
Study Evaluating Etanercept in Subjects With Ankylosing Spondylitis in Spain

Spondylitis Patents:
US Patent No.	Title
7592455	Bicyclic heteroaromatic compounds as kinase inhibitors
7598247	Immunomodulating heterocyclic compounds
7598269	Methods and compositions for treating amyloid-related diseases
7598272	Kinase inhibitors
7598277	Inhibitors of p38
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Companies working in the area of Spondylitis from Bioportfolio's Biocorporate database :
Company Name
Enbrel® (etanercept) Enbrel® (etanercept) is a TNF inhibitor approved for the following indications: moderately to severely active rheumatoid arthritis, polyarticular-course juvenile rheumatoid arthritis, psoriatic... www.enbrel.com        View full profile
Boling Clinical Trials, Inc. Boling Clinical Trials, Inc. is a freestanding clinical trials organization specializing in the therapeutic area of rheumatology and osteoporosis. From its humble beginnings with an occasional... www.bolingclinical.com/        View full profile
ENBREL ENBREL is a type of protein called a tumor necrosis factor (TNF) blocker that blocks the action of a substance your body's immune system makes called TNF. People with an immune disease, such as... www.enbrel.com/        View full profile
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BioPortfolio Ltd. offers e-mail and postal lists for Spondylitis scientists - we have details of around 1402 individuals working on Spondylitis .