Tankyrases

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Recent Publications on Tankyrases:
Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development. Tankyrases are proteins with poly(ADP-ribose) polymerase activity. Human...	10th July, 2008	Experimental Immunology Branch, National Cancer Institute, National	PLoS ONE. 2008 Jul 9;3(7):e2639. DOI Direct Link
Deletion of 8p23.1 with features of Cornelia de Lange syndrome and congenital diaphragmatic hernia and a review of deletions of 8p23.1 to 8pter? A further locus for Cornelia de Lange syndrome. Cornelia de Lange syndrome (CdLS) is characterized by facial dysmorphism;...	17th June, 2008	Genetic Services of Western Australia, Princess Margaret Hospital for	Am J Med Genet A. 2008 Jun 15;146A(12):1565-70. DOI Direct Link
Zinc binding catalytic domain of human tankyrase 1. Tankyrases are recently discovered proteins implicated in many important...	7th June, 2008	Structural Genomics Consortium, Department of Medical Biochemistry and	J Mol Biol. 2008 May 23;379(1):136-45. Epub 2008 Apr 3. DOI Direct Link
Nuclear factor-kappaB activation and differential expression of survivin and Bcl-2 in human grade 2-4 astrocytomas. BACKGROUND: Antiapoptotis resulting from hyperactivation of the...	5th June, 2008	Department of Neuroscience, University of Messina School of Medicine,	Cancer. 2008 May 15;112(10):2258-66. DOI Direct Link
Isolation and physicochemical properties of tankyrase of human embryonic kidney cells of line 293. We have isolated and purified endogenous cytosolic tankyrase from human...	28th May, 2008	Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State	Biochemistry (Mosc). 2008 Mar;73(3):289-95.
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Tankyrases Patents:
US Patent No.	Title
7176188	Method of lethally sensitizing human and animal cells
6977298	Tricyclic inhibitors of poly(ADP-ribose) polymerases
6548494	Tricyclic inhibitors of poly(ADP-ribose) polymerases
6506587	TRF 1 binding protein, methods of use thereof
6277613	TRF1 binding protein, methods of use thereof
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