Tauopathies

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Recent Publications on Tauopathies:
New directions for frontotemporal dementia drug discovery. This report summarizes the recommendations of the Frontotemporal Dementia...	18th July, 2008	Institute on Aging, Center for Neurodegenerative Disease Research,	Alzheimers Dement. 2008 Mar;4(2):89-93. Epub 2007 Sep 10. DOI Direct Link
A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics. The neurofibrillary-tangles (NTFs), characteristic of tauopathies...	18th July, 2008	The Department of Neurology, The Agnes Ginges Center for Human	Exp Neurol. 2008 Jul;212(1):71-84. Epub 2008 Mar 21. DOI Direct Link
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. Pathologic TAR-DNA-binding protein 43 (TDP-43) is a disease protein in...	17th July, 2008	Center for Neurodegenerative Disease Research, Department of Pathology and	J Neuropathol Exp Neurol. 2008 Jun;67(6):555-64. DOI Direct Link
Tauopathy with paired helical filaments in an aged chimpanzee. An enigmatic feature of age-related neurodegenerative diseases is that...	17th July, 2008	Yerkes National Primate Research Center, Emory University, Atlanta,	J Comp Neurol. 2008 Jul 20;509(3):259-70. DOI Direct Link
Tau-based treatment strategies in neurodegenerative diseases. Neurofibrillary tangles are a characteristic hallmark of Alzheimer's and...	16th July, 2008	Department of Psychiatry and Psychotherapy, Von-Siebold-Strasse 5,	Neurotherapeutics. 2008 Jul;5(3):443-57. DOI Direct Link
→View more research publications.

Tauopathies Clinical Trials:
MRS and DTI of White Matter in Alzheimer's Disease	Alzheimer's Disease;   Vascular Dementia

Tauopathies Patents:
US Patent No.	Title
7388005	Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo [1,2-a]pyrimidin-5(1H)one derivatives for neurodegenerative disorders
7161060	Transgenic mice comprising a genomic human tau transgene
7135181	Method for down-regulation of amyloid
7118730	Quinoline derivative as diagnostic probe for disease with tau protein accumulation
7107092	Methods for diagnosing a neurodegenerative condition
→View more patents.

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