Trypanosomiasis

Trypanosomiasis is the name of the several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma. The disease may also be called trypanosomosis but there is no greater authority for either; both terms are widely used in publication. More than 66 million women, men, and children in 36 countries of sub- Saharan Africa suffer from human African trypanosomiasis and 21000 deaths per year associoated with Chagas' disease . There are two forms of African sleeping sickness, caused by two related parasites: * Trypanosoma brucei gambiense* Trypanosoma brucei rhodesiense (From the Wikpedia article Trypanosomiasis.)

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Recent Publications on Trypanosomiasis:
Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei. There is an urgent need for new drugs for the treatment of tropical...	20th November, 2009	Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir	ChemMedChem. 2009 Nov 18. DOI Direct Link
Distribution and Density of Tsetse Flies (Glossinidae: Diptera) at the Game/People/Livestock Interface of the Nkhotakota Game Reserve Human Sleeping Sickness Focus in Malawi. In large parts sub-Saharan Africa, tsetse flies, the vectors of African...	20th November, 2009	Centre for Ticks and Tick-Borne Diseases, Lilongwe, Malawi.	Ecohealth. 2009 Nov 19. DOI Direct Link
Brucellosis presenting as pyrexia of unknown origin in an international traveller: a case report. INTRODUCTION: In this era of globalization frequent traveling across the...	18th November, 2009	Department of Medicine, All India Institute of Medical Sciences New Delhi,	Cases J. 2009 Sep 1;2:7969. DOI Direct Link
Characteristics of the smallholder free-range pig production system in western Kenya. Free-range pig farming is common amongst the small-scale farmers in...	17th November, 2009	Trypanosomiasis Research Centre-KARI, P.O. Box 362, Kikuyu, Kenya,	Trop Anim Health Prod. 2009 Nov 15. DOI Direct Link
Identification of a Parasitic Immunomodulatory Protein Triggering the Development of Suppressive M1 Macrophages during African Trypanosomiasis. Development of classically activated macrophages (M1 cells) is a...	17th November, 2009	Department of Molecular and Cellular Interactions, Vlaams Institute voor	J Infect Dis. 2009 Dec 15;200(12):1849-1860. DOI Direct Link
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BioNews Results for Trypanosomiasis:
East African Trypanosomiasis in a Pregnant Traveler	Center for Disease Control and Prevention:  Oct 23 2009 11:30PM Matching: trypanosomiasis

Trypanosomiasis Patents:
US Patent No.	Title
7495023	Thio semicarbazone and semicarbozone inhibitors of cysteine proteases and methods of their use
7517893	Bichalcophenes and their prodrugs as antiprotozoal agents
7521424	Albumin fusion proteins
7521584	Carotenoid analogs or derivatives for the inhibition and amelioration of disease
7534455	Herbal composition PHY906 and its use in chemotherapy
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BioPortfolio Ltd. offers e-mail and postal lists for Trypanosomiasis scientists - we have details of around 811 individuals working on Trypanosomiasis .