Ubiquitin-Activating Enzymes

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Recent Publications on Ubiquitin-Activating Enzymes:
UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation. Acute promyelocytic leukemia (APL) is characterized by expression of...	19th July, 2008	Department of Pharmacology and Toxicology, Dartmouth Medical School, 7650	Mol Cancer Ther. 2008 Apr;7(4):905-14. DOI Direct Link
Protein interactions in the sumoylation cascade: lessons from X-ray structures. Sumoylation is a multi-step protein modification reaction in which SUMO...	11th July, 2008	Department of Neurochemistry, Max-Planck-Institute for Brain Research,	FEBS J. 2008 Jun;275(12):3003-15. Epub 2008 May 17. DOI Direct Link
Different roles for two ubiquitin-like domains of ISG15 in protein modification. ISG15 (interferon-stimulated gene 15) is a novel ubiquitin-like (UbL)...	18th June, 2008	Institute of Biochemistry and Cell Biology, Shanghai Institutes for	J Biol Chem. 2008 May 9;283(19):13370-7. Epub 2008 Mar 20. DOI Direct Link
Substrate properties of ubiquitin carboxyl-terminally derived peptide probes for protein ubiquitination. Protein ubiquitination is a widespread protein posttranslational...	28th May, 2008	Department of Chemistry, University at Buffalo, The State University of	Biochemistry. 2008 Mar 25;47(12):3636-44. Epub 2008 Feb 29. DOI Direct Link
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. Neuritic retraction represents a prominent feature of the degenerative...	23rd May, 2008	Department of Pathology, Division of Neuropathology, University of	J Neurochem. 2008 May;105(3):1048-56. Epub 2008 Jan 7. DOI Direct Link
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Ubiquitin-Activating Enzymes Patents:
US Patent No.	Title
7223556	Targeted proteolysis by recruitment to ubiquitin protein ligases
5763225	Synthesis of peptides as cloned ubiquitin extensions
5831058	Human GDP dissociation stimulating protein gene
5908973	DNA encoding fruit-ripening-related proteins, DNA constructs, cells and plants derived therefrom
6005088	Human NPIK gene
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