Recent Publications on Ubiquitin-Activating Enzymes: |  |
Proteasome inhibition attenuates coxsackievirus-induced myocardial damage in mice.
Coxsackievirus B3 (CVB3) is one of the most prevalent pathogens of viral...
Direct Link | 22nd August, 2008
| Department of Pathology and Laboratory Medicine, Univ. of British
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Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.
Ubiquitin (Ub) and ubiquitin-like proteins (Ubls) are conjugated to their...
Direct Link | 7th August, 2008
| Department of Biochemistry and Cell Biology, Stony Brook University, Stony
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UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation.
Acute promyelocytic leukemia (APL) is characterized by expression of...
Direct Link | 19th July, 2008
| Department of Pharmacology and Toxicology, Dartmouth Medical School, 7650
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Protein interactions in the sumoylation cascade: lessons from X-ray structures.
Sumoylation is a multi-step protein modification reaction in which SUMO...
Direct Link | 11th July, 2008
| Department of Neurochemistry, Max-Planck-Institute for Brain Research,
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Different roles for two ubiquitin-like domains of ISG15 in protein modification.
ISG15 (interferon-stimulated gene 15) is a novel ubiquitin-like (UbL)...
Direct Link | 18th June, 2008
| Institute of Biochemistry and Cell Biology, Shanghai Institutes for
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Substrate properties of ubiquitin carboxyl-terminally derived peptide probes for protein ubiquitination.
Protein ubiquitination is a widespread protein posttranslational...
Direct Link | 28th May, 2008
| Department of Chemistry, University at Buffalo, The State University of
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Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells.
Neuritic retraction represents a prominent feature of the degenerative...
Direct Link | 23rd May, 2008
| Department of Pathology, Division of Neuropathology, University of
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Synthesis of bisphosphonate derivatives of ATP by T4 DNA ligase, ubiquitin activating enzyme (E1) and other ligases.
T4 DNA ligase and the ubiquitin activating enzyme (E1), catalyze the...
Direct Link | 17th May, 2008
| Departamento de Bioquimica, Instituto de Investigaciones Biomedicas
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Redox-mediated modification of PLZF by SUMO-1 and ubiquitin.
Earlier, we reported that the transcriptional repressor promyelocytic...
Direct Link | 15th May, 2008
| Laboratory of Cellular and Molecular Biochemistry, School of Life Sciences
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Studies of the ubiquitin proteasome system.
A concept that has arisen over the last decade is that proteins can, in...
Direct Link | 14th May, 2008
| National Cancer Institute, Frederick, Maryland, USA.
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Casein kinase 1 alpha associates with the tau-bearing lesions of inclusion body myositis.
Inclusion body myositis and Alzheimer's disease are age-related disorders...
Direct Link | 3rd May, 2008
| Center for Molecular Neurobiology, Department of Molecular and Cellular
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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.
We demonstrate a role for the NAD-dependent deacetylase Sirt1 in the...
Direct Link | 19th April, 2008
| Translational Medicine Branch, National Heart, Lung, and Blood Institute,
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Cellular proteasome activity facilitates herpes simplex virus entry at a postpenetration step.
Herpes simplex virus (HSV) entry into cells is a multistep process that...
Direct Link | 16th April, 2008
| Department of Microbiology and Immunology, Virginia Commonwealth
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Comprehensive proteomics analysis of autophagy-deficient mouse liver.
Autophagy is a bulk protein degradation system for the entire organelles...
Direct Link | 9th April, 2008
| Department of Biochemistry, Juntendo University School of Medicine, 2-1-1
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Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.
Ubiquitin-like proteins (UBLs) modify targets via related E1-E2-E3...
Direct Link | 26th March, 2008
| Howard Hughes Medical Institute, St. Jude Children's Research Hospital,
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