Recent Publications on Uracil-DNA Glycosidase: |  |
Ion pairs and their role in modulating stability of cold- and warm-active uracil DNA glycosylase.
MD simulations and continuum electrostatics calculations have been used to...
Direct Link | 16th August, 2008
| The Norwegian Structural Biology Centre, Department of Chemistry,
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Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
Folate deficiency and resultant increased homocysteine levels have been...
Direct Link | 13th August, 2008
| Klinik und Poliklinik fur Neurologie, Center for Stroke Research Berlin,
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| Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase.
| 13th August, 2008
| Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal
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Protein surface conservation in binding sites.
An algorithm is described which uses the conservation of the 3D structure...
Direct Link | 31st July, 2008
| National Institute of Chemistry, Ljubljana, Slovenia.
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Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources.
Uracil-DNA glycosylase (UNG), a repair enzyme involved in the excision of...
Direct Link | 1st July, 2008
| Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012,
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Human APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1.
APOBEC3 proteins are mammal-specific cytidine deaminases that can restrict...
Direct Link | 24th June, 2008
| Medical Research Council Laboratory of Molecular Biology, Hills Road,
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Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase.
Thymidylate synthase (TS) is an important target of several...
Direct Link | 14th May, 2008
| Department of Pharmaceutical and Biomedical Sciences, South Carolina
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Electrostatic interactions play an essential role in DNA repair and cold-adaptation of uracil DNA glycosylase.
Life has adapted to most environments on earth, including low and high...
Direct Link | 22nd April, 2008
| The Norwegian Structural Biology Centre, Department of Chemistry,
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Correlated cleavage of single- and double-stranded substrates by uracil-DNA glycosylase.
Uracil-DNA glycosylase (Ung) can quickly locate uracil bases in an excess...
Direct Link | 9th April, 2008
| SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk
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Two levels of protection for the B cell genome during somatic hypermutation.
Somatic hypermutation introduces point mutations into immunoglobulin genes...
Direct Link | 20th March, 2008
| Department of Immunobiology, Yale University School of Medicine, New
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Molecular cloning of PCR products.
It is often desirable to clone PCR products to establish a permanent...
Direct Link | 14th March, 2008
| MJ Research, Watertown, Massachusetts, USA.
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| Bacterial beta-lactamase fragmentation complementation strategy can be used as a method for identifying interacting protein pairs.
| 29th February, 2008
| Department of Advanced Technology Fusion and Bio/Molecular Informatics
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Methylation and uracil interference assays for analysis of protein-DNA interactions.
Interference assays identify specific residues in the DNA binding site...
Direct Link | 22nd February, 2008
| University of North Carolina, Chapel Hill, North Carolina, USA.
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High rate of starvation-associated mutagenesis in Ung(-) yeast caused by the overproduction of human activation-induced deaminase.
We examined the role of Saccharomyces cerevisiae uracil DNA glycosylase in...
Direct Link | 1st February, 2008
| Dipartimento di Biologia Cellulare e Ambientale, Universita di Perugia,
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| Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
| 7th December, 2007
| Department of Molecular Genetics and Microbiology, Program in Immunology
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