Uracil Nucleotides

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Recent Publications on Uracil Nucleotides:
Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. The phosphate, uracil, and ribose moieties of uracil nucleotides were...	17th July, 2008	Molecular Recognition Section, Laboratory of Bioorganic Chemistry, NIDDK,	Bioorg Med Chem. 2008 Jun 15;16(12):6319-32. Epub 2008 May 9. DOI Direct Link
Stereospecific synthesis of sugar-1-phosphates and their conversion to sugar nucleotides. As Leloir glycosyltransferases are increasingly being used to prepare...	3rd June, 2008	Department of Chemistry, Dalhousie University, Halifax, Nova Scotia,	Carbohydr Res. 2008 Apr 7;343(5):865-74. Epub 2008 Feb 9. DOI Direct Link
UDP is a competitive antagonist at the human P2Y14 receptor. G protein-coupled P2Y receptors (P2Y-R) are activated by adenine and...	20th May, 2008	Department of Pharmacology, University of North Carolina, CB#7365 Mary	J Pharmacol Exp Ther. 2008 May;325(2):588-94. Epub 2008 Feb 5. DOI Direct Link
Uracil nucleotides: from metabolic intermediates to neuroprotection and neuroinflammation. Uracil nucleotides (i.e., UTP and UDP) have been known for years as...	17th May, 2008	Laboratory of Molecular and Cellular Pharmacology of Purinergic	Biochem Pharmacol. 2008 May 15;75(10):1869-81. Epub 2008 Jan 3. DOI Direct Link
Opposite effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes. We previously showed that the human heart expresses all known P2X and P2Y...	19th April, 2008	Laboratory of Molecular and Cellular Pharmacology of Purinergic	J Cell Mol Med. 2008 Mar-Apr;12(2):522-36. DOI Direct Link
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Uracil Nucleotides Patents:
US Patent No.	Title
5583117	Acylated uridine and cytidine for elevating tissue uridine and cytidine
6258795	Acylated uridine and cytidine and uses thereof
6274563	Acylated uridine and cytidine and uses thereof
6294655	Anti-interleukin-1 receptor antagonist antibodies and uses thereof
6316426	Acylated uridine and cytidine and uses thereof
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