Urate Oxidase

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Recent Publications on Urate Oxidase:
Pegloticase, a polyethylene glycol conjugate of uricase for the potential intravenous treatment of gout. Savient Pharmaceuticals Inc (formerly Bio-Technology General Corp), under...	11th July, 2008	West Virginia University School of Medicine, Robert C Byrd Health Sciences	Curr Opin Investig Drugs. 2008 Apr;9(4):422-9.
Site-Specific Incorporation of Unnatural Amino Acids into Urate oxidase in Escherichia coli. Urate oxidase catalyzes the oxidation of uric acid with poor solubility to...	4th July, 2008		Protein Sci. 2008 Jul 2;. DOI Direct Link
Efficacy and (pharmaco)kinetics of one single dose of rasburicase in patients with chronic kidney disease. AIMS: Hyperuricemia is a risk factor associated with cardiovascular and...	3rd July, 2008	Department of Nephrology, Dialysis and Hypertension, Malpighi Hospital,	Nephron Clin Pract. 2008;108(4):c265-71. Epub 2008 Apr 17. DOI Direct Link
SFCE (Societe Francaise de Lutte contre les Cancers et Leucemies de l'Enfant et de l'Adolescent) recommendations for the management of tumor lysis syndrome (TLS) with rasburicase: an observational survey. Rasburicase (Fasturtec), a recombinant urate oxidase, is highly effective...	5th June, 2008	Service d'Hematologie Pediatrie, Hopital Debrousse, Lyon, France.	J Pediatr Hematol Oncol. 2008 Apr;30(4):267-71. DOI Direct Link
[New antihyperuricemic medicine: febuxostat, Puricase, etc] An inhibitor of xanthine dehydrogenase (XDH), allopurinol, and uricosuric...	31st May, 2008	Department of Pathophysiology, Tokyo University of Pharmacy and Life	Nippon Rinsho. 2008 Apr;66(4):759-65.
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BioNews Results for Urate Oxidase:
High urate levels seen slowing Parkinson's disease	Reuters UK:  Apr 14 2008 9:06PM Matching: urate

Urate Oxidase Clinical Trials:
Rasburicase as a Uricolytic Therapy for Hyperuricemia in Patients With Leukemia or Lymphoma	Hyperuricemia;   Leukemia;   Lymphoma
Treatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lymphoma	Adult Acute Lymphocytic Leukemia;   High-Grade Lymphoma
Rasburicase for Treatment of Hyperuricemia in Children and Adolescence Patients With Tumor Lysis Syndrome	Hyperuricemia Intervention: Drug: Rasburicase
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma	Drug/Agent Toxicity by Tissue/Organ;   Leukemia;   Lymphoma
Rasburicase Treatment for Chemotherapy or Malignancy-Induced Hyperuricemia in Asthma/Allergy Patients	Leukemia;   Lymphoma;   Tumor Lysis Syndrome;   Hyperuricemia
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Urate Oxidase Patents:
US Patent No.	Title
6960323	Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
7037647	Prostate-specific membrane antigen and uses thereof
7056713	Urate oxidase
7070782	Prostate-specific membrane antigen
7083792	Immunologically active proteins from Borrelia burgdorferi
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