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Uridine Phosphorylase

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Recent Publications on Uridine Phosphorylase:

Pubmed Logo
Induction of nucleoside phosphorylase in Enterobacter aerogenes and enzymatic synthesis of adenine arabinoside.
Nucleoside phosphorylases (NPases) were found to be induced in...
5th July, 2008
College of Biotechnology, Tianjin University of Science and Technology, J Zhejiang Univ Sci B. 2008 Jul;9(7):520-526.
DOI Direct Link
Multiple pathways are involved in drug resistance to doxorubicin in an osteosarcoma cell line.
Drug resistance continues to be a stumbling block in achieving a better...
20th June, 2008
Department of Molecular Oncology, Cancer Institute (WIA), Adyar, Chennai Anticancer Drugs. 2008 Mar;19(3):257-65.
Effects of Combined Administration of DPD-Inhibitory Oral Fluoropyrimidine, S-1, Plus Paclitaxel on Gene Expressions of Fluoropyrimidine Metabolism-Related Enzymes in Human Gastric Xenografts.
BACKGROUND: S-1 is the most effective oral fluoropyrimidine derivative...
29th May, 2008
Department of Surgery, Fujita Health University School of Medicine, 1-98 Ann Surg Oncol. 2008 May 28;.
DOI Direct Link
The iscS gene deficiency affects the expression of pyrimidine metabolism genes.
Inactivation of iscS encoding cysteine desulfurase results in a slow...
17th May, 2008
Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto Biochem Biophys Res Commun. 2008 Aug 1;372(3):407-11. Epub 2008 May 13.
DOI Direct Link
Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase.
ABSTRACT We previously reported that uridine blocked glucose...
7th May, 2008
College of Pharmacy, Seoul National University, Seoul, Korea. J Neurotrauma. 2008 Jun;25(6):695-707.
DOI Direct Link

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Uridine Phosphorylase Clinical Trials:

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A Study of ADH300004 in Surgically Resected Primary or Metastatic Colorectal Cancer and Liver Biopsy, or Planned Hepatic Resection
Neoplasms Intervention: Drug: ADH300004

Uridine Phosphorylase Patents:

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US Patent No.Title
6586440 Pharmaceutical compositions of 5-alkynyl uracil compounds
6841345 Treatment and prevention of immunodeficiency virus infection by administration of non-pyrogenic derivatives of lipid A
6846651 Nucleotide sequence of the Haemophilus influenzae Rd genome, fragments thereof, and uses thereof
6861059 Methods and compositions for treatment of HIV-1 infection using antiviral compounds in simultaneous or sequential combinations
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases

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Wikipedia excerpt, where present, licenced under the GNU Free Documentation License. Resources from the NCBI applied. Selected MeSH subject headings created and maintained by the US NLM are used in conjunction with additional keywords. 2006-2008 MeSH.
 

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