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Vault Ribonucleoprotein Particles

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Recent Publications on Vault Ribonucleoprotein Particles:

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Pharmacological effects of serum containing chinese medicine Bushen Huayu Jiedu Compound Recipe in lung cancer drug-resistance cells.
OBJECTIVE: To explore the pharmacologic effects of Chinese medicine Bushen...
9th July, 2008
Department of Traditional Chinese Medicine, Jinan University Medical Chin J Integr Med. 2008 Mar;14(1):46-50.
DOI Direct Link
A vault ribonucleoprotein particle exhibiting 39-fold dihedral symmetry.
Vault is a 12.9 MDa ribonucleoprotein particle with a barrel-like shape,...
1st July, 2008
Insutitute for Protein Research, Osaka University, 3-2 Yamada-oka, Suita Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):525-31. Epub 2008
DOI Direct Link
Determination of P-glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia.
BACKGROUND: The most primitive leukemic precursor in acute myeloid...
5th June, 2008
Hematology Division, Department of Internal Medicine, Medical School of Cytometry B Clin Cytom. 2008 May;74(3):163-8.
DOI Direct Link
Expression of multidrug-resistance-related proteins P-glycoprotein, glutathione-S-transferases, topoisomerase-II and lung resistance protein in primary gastric cardiac adenocarcinoma.
AIM: Multidrug resistance (MDR) is closely correlated to an unfavorable...
3rd June, 2008
Department of Cardiothoracic Surgery, Clinical College, Yangzhou Cancer Invest. 2008 May;26(4):344-51.
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CD34+ leukemic subpopulation predominantly displays lower spontaneous apoptosis and has higher expression levels of Bcl-2 and MDR1 genes than CD34- cells in childhood AML.
In view of obscure clinical and biological significance of leukemic cells...
28th May, 2008
Belarusian Research Center for Pediatric Oncology and Hematology, Minski Ann Hematol. 2008 May;87(5):353-60. Epub 2008 Jan 29.
DOI Direct Link

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Vault Ribonucleoprotein Particles Patents:

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US Patent No.Title
6852535 Polymerase III-based expression of therapeutic RNAS
5877162 Short external guide sequences
5902880 RNA polymerase III-based expression of therapeutic RNAs
6013447 Random intracellular method for obtaining optimally active nucleic acid molecules
6057153 Stabilized external guide sequences

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