Recent Publications on Vdj Exons: |  |
The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions.
The immunoglobulin heavy-chain (Igh) locus is organized into distinct... Direct Link | 29th April, 2008
| Division of Biological Sciences, 0377, University of California, San
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Does antisense make sense of AID targeting?
The immunoglobulin heavy-chain (Igh) locus is organized into distinct... Direct Link | 9th April, 2008
| Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY
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Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions.
Activation-induced cytosine deaminase (AID) is essential for both somatic... Direct Link | 9th April, 2008
| The Howard Hughes Medical Institute, The Children's Hospital, Immune
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The endless tale of non-homologous end-joining.
DNA double-strand breaks (DSBs) are introduced in cells by ionizing... Direct Link | 9th February, 2008
| Department of Radiation Oncology, Division of Molecular Radiation Biology,
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Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune system.
Nonhomologous DNA end joining (NHEJ) is the primary pathway for repair of... Direct Link | 9th February, 2008
| USC Norris Comprehensive Cancer Center, University of Southern California
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| Molecular characterization of complete and incomplete immunoglobulin heavy chain gene rearrangements in hairy cell leukemia.
| 31st January, 2008
| Servicio de Hematologia, Hospital Universitario de Salamanca, Centro de
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| Molecular methods used for the detection of autologous graft contamination in lymphoid disorders.
| 24th October, 2007
| Istituto Nazionale per lo Studio e la Cura dei Tumori, Universita degli
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B lymphocyte deficiency in IgH-transgenic rabbits.
We developed IgH-transgenic rabbits carrying a productive VDJ-Cmu Tg and... Direct Link | 22nd September, 2007
| Department of Microbiology and Immunology, Loyola University Chicago,
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| Expression of SNC73, a transcript of the immunoglobulin alpha-1 gene, in human epithelial carcinomas.
| 21st August, 2007
| Cancer Institute, Zhejiang University School of Medicine, The Second
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| Molecular characterization of heavy chain immunoglobulin gene rearrangements in Waldenstrom's macroglobulinemia and IgM monoclonal gammopathy of undetermined significance.
| 17th July, 2007
| Servicio de Hematologia, Hospital Universitario de Salamanca, Spain.
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An alternative branch of the nonsense-mediated decay pathway.
The T-cell receptor (TCR) locus undergoes programmed rearrangements that... Direct Link | 15th May, 2007
| Department of Biochemistry and Molecular Biology, The University of Texas
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Expression and secretion of immunoglobulin alpha heavy chain with diverse VDJ recombinations by human epithelial cancer cells.
Generally, only B lymphocytes express immunoglobulin. Recently, we found... Direct Link | 12th April, 2007
| Cancer Research Institute, Xiangya Medicine School, Central South
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Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell lymphoma.
Mantle cell lymphoma (MCL) is typically composed of small irregular... Direct Link | 7th April, 2007
| Department of Hematopathology, The University of Texas MD Anderson Cancer
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| VH replacement rescues progenitor B cells with two nonproductive VDJ alleles.
| 6th January, 2007
| Division of Molecular Immunology, Department of Internal Medicine III,
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Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations.
When a single double-strand break arises in the genome, nonhomologous DNA... Direct Link | 12th December, 2006
| USC Norris Comprehensive Cancer Ctr., Rm. 5428, University of Southern
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