Recent Publications on Vdj Recombinases: |  |
| A RAG1 mutation found in Omenn syndrome causes coding flank hypersensitivity: a novel mechanism for antigen receptor repertoire restriction.
| 19th November, 2008
| Program in Molecular Pathogenesis, Helen L. and Martin S. Kimmel Center
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Quantitative analyses of RAG-RSS interactions and conformations revealed by atomic force microscopy.
During V(D)J recombination, site specific DNA excision is dictated by the...
Direct Link | 15th November, 2008
| School of Life Sciences, Center for Infectious Disease and Vaccinology,
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Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.
The transcription factor Ikaros is essential for B cell development....
Direct Link | 10th October, 2008
| Howard Hughes Medical Institute, Department of Molecular Genetics and Cell
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Chromosomal translocations in childhood leukemia: natural history, mechanisms, and epidemiology.
The root causes of childhood leukemia will be discovered by understanding...
Direct Link | 25th September, 2008
| Department of Epidemiology and Biostatistics, University of California,
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Mechanistic aspects of lymphoid chromosomal translocations.
Chromosomal translocations require double-strand breakage at two sites,...
Direct Link | 25th September, 2008
| USC Norris Comprehensive Cancer Center, Department of Pathology,
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| Differential activation of dual promoters alters Dbeta2 germline transcription during thymocyte development.
| 14th August, 2008
| Department of Microbiology, North Carolina State University, Raleigh, NC
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| Functional analysis of histone methyltransferase g9a in B and T lymphocytes.
| 29th July, 2008
| Department of Microbiology and Immunology, Vanderbilt University,
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Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition.
Antigen receptor variable-(diversity)-joining (V(D)J) recombination at the...
Direct Link | 17th July, 2008
| Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell
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| ATM prevents unattended DNA double strand breaks on site and in generations to come.
| 17th July, 2008
| Department of Pathology and Laboratory Medicine, Children's Hospital of
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Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition.
The Rag1 and Rag2 proteins initiate V(D)J recombination by introducing...
Direct Link | 14th June, 2008
| Program in Molecular Pathogenesis, Department of Pathology, New York
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V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies.
V(D)J recombination is a process integral to lymphocyte development....
Direct Link | 21st May, 2008
| Department of Medical Microbiology and Immunology, Creighton University
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Thermal dependency of RAG1 self-association properties.
BACKGROUND: Functional immunoglobulin and T cell receptor genes are...
Direct Link | 16th April, 2008
| Department of Biochemistry and Molecular Biology, The University of
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| The ontogeny and fate of NK cells marked by permanent DNA rearrangements.
| 18th March, 2008
| Department of Immunology, University of Pittsburgh School of Medicine, 200
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V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.
The immune system is the site of intense DNA damage/modification, which...
Direct Link | 11th January, 2008
| INSERM, U768, Paris, France.
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Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly.
Double-strand breaks (DSBs) are intermediates in several physiological...
Direct Link | 11th January, 2008
| Experimental Immunology Branch, National Cancer Institute, National
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