Von Hippel-Lindau Tumor Suppressor Protein

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Recent Publications on Von Hippel-Lindau Tumor Suppressor Protein:
The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. The von Hippel-Lindau disease is caused by inactivating germline mutations...	19th November, 2008	Howard Hughes Medical Institute, Chevy Chase, Maryland 20815-6789, USA.	Nat Rev Cancer. 2008 Nov;8(11):865-73. Epub 2008 Oct 16. DOI Direct Link
Targeted therapy for the loss of von Hippel-Lindau in renal cell carcinoma: a novel molecule that induces autophagic cell death. Radiation and conventional cytotoxic chemotherapies are ineffective in...	18th November, 2008	Department of Radiation Oncology, Stanford University School of Medicine,	Autophagy. 2008 Oct 1;4(7):944-6. Epub 2008 Oct 13.
Two hypoxia sensor genes and their association with symptoms of acute mountain sickness in Sherpas. INTRODUCTION: Hypoxia-inducible factor (HIF) and von Hippel-Lindau tumor...	13th November, 2008	Department of Medicine, Shinshu University School of Medicine, Matsumoto,	Aviat Space Environ Med. 2008 Nov;79(11):1056-60.
Reduced expression of von Hippel-Lindau gene in subjects exposed to polychlorinated biphenyls and dibenzofurans. Polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs)...	13th November, 2008	Environmental and Occupational Health, College of Medicine, National	Environ Res. 2008 Oct;108(2):247-51. Epub 2008 Aug 22. DOI Direct Link
Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells. Here, we provide the first evidence that sphingosine kinase 1 (SphK1), an...	8th November, 2008	Centre National de la Recherche Scientifique, Sphingolipids and Cancer	Cancer Res. 2008 Oct 15;68(20):8635-42. DOI Direct Link
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Von Hippel-Lindau Tumor Suppressor Protein Patents:
US Patent No.	Title
7442781	Diagnosis, prevention and treatment of cancer
7078174	Screening methods using SOCS box-containing peptides
7074908	Protein specific for cardiac and skeletal muscle
7053046	Peptide activators of VEGF
6858709	Component of von Hippel-Lindau tumor suppressor complex and SCF ubiquitin ligase
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