Wakefulness

Wakefulness refers to the state of being awake and is the behavioral manifestation of the metabolic state of catabolism. It is the daily recurring period in an organism's life during which consciousness, awareness and all behaviors necessary for survival, i.e., success in , are conducted. Being awake is the opposite of being asleep a behavioral manifestation of the daily recurring metabolic state of anabolism. Animals can eat and run, fly, swim or walk while awake; humans can also talk, listen, write, read, and productively think and work in the awake state. It is self-evident that the behaviors which take place while an organism is awake are necessary, complex, interesting and diverse. As sleep is biologically necessary, an excess of time spent awake is considered sleep deprivation, and there are serious physiological and psychological consequences both for individual stretches of wakefulness and serial preference for wakeful activity rather than sleep. (From the Wikpedia article Wakefulness.)

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Recent Publications on Wakefulness:
[A novel proposal explaining sleep disturbance of children in Japan--asynchronization] It has been reported that more than half of the children in Japan suffer...	19th July, 2008	Tokyo Kita	No To Hattatsu. 2008 Jul;40(4):277-83.
Molecular mechanisms of sleep and wakefulness. Major questions on the biology of sleep include the following: what are...	19th July, 2008	Center for Sleep and Respiratory Neurobiology, Division of Sleep	Ann N Y Acad Sci. 2008;1129:335-49. DOI Direct Link
Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice. Internal brain states form key determinants for sensory perception,...	18th July, 2008	Laboratory of Sensory Processing, Brain Mind Institute, Faculty of Life	Nature. 2008 Jul 16;. DOI Direct Link
Histamine in the nervous system. Histamine is a transmitter in the nervous system and a signaling molecule...	16th July, 2008		Physiol Rev. 2008 Jul;88(3):1183-241. DOI Direct Link
Effect of 17alpha-ethinyl estradiol on active phase rapid eye movement sleep microarchitecture. Estrogen treatment decreases active phase rapid eye movement (REM) sleep...	16th July, 2008	Women's Health & Musculoskeletal Biology, Wyeth Research, Collegeville, PA	Eur J Pharmacol. 2008 Jun 27;. DOI Direct Link
→View more research publications.

BioNews Results for Wakefulness:
New Research on Insomnia	Consultant Live:  Jun 11 2008 4:07PM Matching: wakefulness

Wakefulness Clinical Trials:
Progesterone Reduces Wakefulness in Sleep EEG and Has no Effect on Cognition in Healthy Postmenopausal Women	Healthy;   Postmenopausal

Wakefulness Patents:
US Patent No.	Title
7304086	Inhibitors of glutaminyl cyclase
7332486	Phosphodiesterase 4 inhibitors
7332508	Substituted homopiperidine, piperidine or pyrrolidine derivatives
7335640	Administration of hypocretin-1 for treatment of narcolepsy
7335654	Phosphodiesterase 4 inhibitors
→View more patents.

Companies working in the area of Wakefulness from Bioportfolio's Biocorporate database :
Company Name
The Center for Sleep & Wake Disorders The Center for Sleep & Wake Disorders is a full service sleep center caring for patients with all disorders of sleep and wakefulness. Patients enjoy the advantages of an expertly trained staff, the... www.sleepdoc.com/        View full profile

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