Recent Publications on Xenograft Model Antitumor Assays: |  |
T40214/PEI complex: a potent therapeutics for prostate cancer that targets STAT3 signaling.
BACKGROUND: Prostate cancer (PC) is the most common cancer among men in...
Direct Link | 6th September, 2008
| Department of Medicine, Baylor College of Medicine, Houston, Texas 77030,
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Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors.
PURPOSE: To assess the effects of noscapine, a tubulin-binding drug, in...
Direct Link | 5th September, 2008
| Department of Pathology, New York University School of Medicine, 550 First
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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.
The discovery of new small molecules and their testing in rational...
Direct Link | 4th September, 2008
| Department of Pediatric Oncology, Dana-Farber Cancer Institute and
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Nanoparticle-mediated gene delivery to the lung.
Drug delivery, especially gene delivery to the lung, has been a challenge....
Direct Link | 30th August, 2008
| Department of Thoracic and Cardiovascular Surgery, The University of Texas
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| Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells in vivo.
| 30th August, 2008
| Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota
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4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase.
4-(1,3-Thiazol-2-yl)morpholine derivatives have been identified as potent...
Direct Link | 23rd August, 2008
| Department of Medicinal Chemistry, UCB, 208 Bath Road, Slough, Berkshire
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Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway.
Caspase-3 is known as a cysteine protease that primarily executes the cell...
Direct Link | 23rd August, 2008
| Department of Microbiology and Immunology, National Cheng Kung University,
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Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode.
A piperazine series of cyclin-dependent kinase (CDK) inhibitors have been...
Direct Link | 23rd August, 2008
| Cancer and Infection Research Area, AstraZeneca Pharmaceuticals, Alderley
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Increased suppression of oncolytic adenovirus carrying mutant k5 on colorectal tumor.
Angiogenesis plays a key role in the development of a wide variety of...
Direct Link | 22nd August, 2008
| Institute of Biochemistry and Cell Biology, Shanghai Institutes for
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Combination treatment of human umbilical cord matrix stem cell-based interferon-beta gene therapy and 5-fluorouracil significantly reduces growth of metastatic human breast cancer in SCID mouse lungs.
Umbilical cord matrix stem (UCMS) cells that were engineered to express...
Direct Link | 15th August, 2008
| Department of Anatomy & Physiology, Kansas State University, Manhattan,
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Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis.
Integrin alphanubeta3 is found on a subset of tumor blood vessels where it...
Direct Link | 9th August, 2008
| Department of Pathology, Moores Cancer Center, University of California at
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| Changes of gene expression of thymidine phosphorylase, thymidylate synthase, dihydropyrimidine dehydrogenase after the administration of 5'-deoxy-5-fluorouridine, paclitaxel and its combination in human gastric cancer xenografts.
| 26th July, 2008
| Department of Surgery, Fujita Health University School of Medicine,
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| Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines.
| 26th July, 2008
| Department of Orthopaedic Surgery, Graduate School of Medical Sciences,
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| The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis.
| 26th July, 2008
| Department of Medical Cell Biology, Children's Hospital, Uppsala
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| A comparison of two orally bioavailable anti-cancer agents, IRC-110160 and STX140.
| 26th July, 2008
| Endocrinology and Metabolic Medicine and Sterix Ltd., Faculty of Medicine,
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