p21-Activated Kinases

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Recent Publications on p21-Activated Kinases:
Myotonic dystrophy protein kinase (DMPK) and its role in the pathogenesis of myotonic dystrophy 1. Myotonic dystrophy 1 (DM1) is an autosomal, dominant inherited,...	28th June, 2008	Institut d'Investigacions Biomediques August Pi i Sunyer	Cell Signal. 2008 May 18;. DOI Direct Link
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Autoregulatory domains found within kinases may provide more unique...	26th June, 2008	Basic Sciences Division, Fox Chase Cancer Center, Philadelphia, PA 19111,	Chem Biol. 2008 Apr;15(4):322-31. DOI Direct Link
PAK'n it in: identification of a selective PAK inhibitor. p21-activated kinases are important signaling kinases for which no...	26th June, 2008	Departments of Immunology and Cell Biology, The Scripps Research	Chem Biol. 2008 Apr;15(4):305-6. DOI Direct Link
Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. There is now considerable experimental evidence that aberrant activation...	21st June, 2008	University of North Carolina at Chapel Hill, Lineberger Comprehensive	Methods Enzymol. 2008;439:111-29. DOI Direct Link
ROCK, PAK, and Toll of synapses in Alzheimer's disease. Alzheimer's disease is a neurodegenerative disorder where the cognitive...	19th June, 2008	Department of Neurology, Institute of Clinical Medicine, University of	Biochem Biophys Res Commun. 2008 Jul 11;371(4):587-90. Epub 2008 May 6. DOI Direct Link
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p21-Activated Kinases Patents:
US Patent No.	Title
7378498	Protein encoded by a nucleic acid
6645728	Inhibitor of the inflammatory response induced by TNF.alpha. and IL-1
6599726	Compositions and methods comprising cytostatic protein kinase
6586242	TAO protein kinases and methods of use therefor
6555325	System for detection of a functional interaction between a compound and a cellular signal transduction component
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