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Catachem Introduces the Total Bile Acids (TBA) In-Vitro Diagnostic (IVD) Chemistry Reagent Kit

Bridgeport, Connecticut, USA (November 28, 2003)…. Catachem, Inc. (Catachem, Private) today announced the addition of the Total Bile Acids (TBA) in vitro diagnostic chemistry reagent kit to Catachem’s product line of over 30 chemistries and more than 100 products.

 

Total bile acids are metabolized in the liver and hence serve as a marker for normal liver function. Serum total bile acids are increased in patients with acute hepatitis, chronic hepatitis, liver sclerosis and liver cancer. TBA is measured in the presence of Thio-NAD, the enzyme 3-a hydroxysteroid dehydrogenase (3-a HSD) which converts bile acids to 3-keto steroids and Thio-NADH. The reaction is reversible and 3-a HSD can convert 3-keto steroids and Thio-NADH to bile acids and Thio-NAD. In the presence of excess NADH, the enzyme cycling occurs efficiently and the rate of formation of Thio-NADH is determined by measuring specific change of absorbance at 405 nm. TBA is a two reagent chemistry available in one size. Reagents are packaged ready-to-use in plastic wedge bottles. Calibrator and controls are available separately. TBA Kit PN CC042A performs 440 tests and TBA Control PN CC042A-C1 is 1 mL.

Benjamin Twombly, Vice President Sales and Marketing, commented, “We currently have an extremely popular Bile Acids assay and the addition of this new Total Bile Acids assay to our Liver Panel will provide more comprehensive services for our customers.”  Luis P. Leon, President, commented, “We are pleased to add this assay to our growing product line.”

About Catachem, Inc.

Catachem has a rich 20 year history in clinical chemistry as a manufacturer and distributor of in-vitro chemistry products and services for human, veterinary and environmental laboratories. Catachem chemists helped develop many of the automated diagnostic chemistries widely in use today.  Catachem created the DiscretePak™ and VetSpec™ line of reagents for human and veterinary automated analyzers.  Catachem offers FDA approved (510K) chemistries (liquid and dry) including enzymatic chemistries developed in conjunction with IFCC and CDC.  Catachem has more than 500 applications for all types of analyzers including the Roche, Hitachi, Olympus, AU Series, RA Series, Opera, DAX, Bayer, Advia, Synchron, Beckman, Abbott and many other analyzers.  Corporate headquarters, research, custom formulation laboratories, and manufacturing are located in Bridgeport, Connecticut.  Catachem supplies leading laboratories and equipment manufacturers from distributors around the world. 

Forward-looking statements in this release are made pursuant to the ``safe harbor'' provision of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that such forward-looking statements involve risks and uncertainties including, but not limited to, the results of research and development efforts, the effect of regulation by the United States Food and Drug Administration and other agencies, the impact of competitive products, product development commercialization and technological difficulties, and other risks detailed in the Company's periodic reports filed with the Securities and Exchange Commission.

Keywords: Catachem, Chemistry, Reagents, In-Vitro Diagnostics, IVD, Veterinary, Total Bile Acids, TBA

For more information contact:

Benjamin Twombly
Catachem, Inc.
70 Hawley Avenue
Bridgeport, CT
USA 06606
+1 (203) 335-9277 Office
+1 (203) 335-9977 FAX
bentwombly@aol.com
catachem@aol.com
www.catacheminc.com

Ref: C3005d

Catachem chemistries include: 5'-Nucleotidase (5NT), Adenosine Deaminase (ADA), Alanine Aminotransferase (ALT), Albumin BCG (ALB), a-L-Fucosidase (AFU), Alkaline Phosphatase (ALP), Ammonia (NH), Amylase (AMY), Aspartate Aminotransferase (ALP), β-Hydroxybutyrate (BHBA), Bicarbonate (HC03), Bile Acids (BA), Bilirubin, Direct with Blank (DBILI), Bilirubin, Total with Blank (TBILI), Bilirubin, Total (TBILI), Blood Urea Nitrogen (BUN), Bromide (BR), CO2 [340] (CO2), CO2 [380] (CO2), CO2 [single reagent] (CO2), Ca+++ Arsenazo [650NM] (CA3), Chloride [340 NM] (CL), Cholesterol (CH), Creatine Kinase (CK), Creatinine (CREAT), Fructosamine [millimole method] (FR), Fructosamine, Glycated Serum Protein [enzymatic] (FR), Gamma-Glutamyl Transpeptidase (GGT), Glucose Hexokinase (GLU), Glycated Hemoglobin (HbA1c), High Density Lipoproteins, Dextran Sulfate (HDL), Inorganic Phosphorus (IP), Lactate Dehydrogenase (LD), Lipase (LIP), Lithium [enzymatic] (LI), Magnesium (MG), N-Acetyl-ß-D-glucosaminidase (NAG), Potassium [enzymatic] (K), Plasma Free Hemoglobin (PFH), Pre-albumin (TBPA), Sodium [enzymatic] (NA), Sorbitol Dehydrogenase (SDH), Thiopurine methyltransferase (TPMT), Total Bile Acids (TBA), Total Iron (TI), Total Protein (TP), Triglycerides (TRIG), UIBC and TIBC (UIBC), Uric Acid (UA), Vitamin B6 (V6B), Multipoint Calibrator Catacal, Catatrol Level 1 Catatrol Level 2, Bile Acids Control, Bile Acids Calibrator, BHBA Calibrator, BHBA Control Level 1, BHBA Control Level 2; Bromide Calibrator, BR Control Level 1, BR Control Level 2; Fructosamine Calibrator, FR Control Level 1, FR Control Level 2, SDH Control Level 1, SDH  Control Level 2.  Call +1 (203) 335-9277 or Write Catachem@aol.com.

 

 

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