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Showing "antibody antibodies immunoglobulin" News Articles 1 to 25 of 4,100+
In The Most Severe Form Of Rheumatoid Arthritis, Enzyme-Activating Antibodies Identified As A Marker
In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system make...
A preclinical anti-TLR3 candidate in IPH33 (anti-inflammatory) has been selected for preclinical studies, which is now ready for partnering. Meanwhile, an IPH41 (anti-cancer) anti-KIR3DL2 candidate should be selected by the end of 2013. Lead product, anti-KIR antibody lirilumab (IPH2102), is in a Phase II trial for acute myeloid leukaemia (AML) and in two Phase I trials for solid cancers. One tr...
Powerful new method for finding therapeutic antibodies
Scientists at The Scripps Research Institute (TSRI) have devised a powerful new technique for finding antibodies that have a desired biological effect. Antibodies, which can bind to billions of distinct targets, are already used in many of the world...
Huahai and Oncobiologics make biosimilars deal
US-based Oncobiologics announced on 8 May 2013 that it had signed an alliance agreement for the development, manufacture and commercialization of biosimilar monoclonal antibodies with Zhejiang Huahai Pharmaceutical (Huahai).
MedImmune and KineMed study protein dynamics related to neurodegenerative diseases
MedImmune and KineMed Inc have formed an agreement to study how a monoclonal antibody affects the dynamics of the cellular prion protein (PrPc), which is known to have altered conformation and function in several neurodegenerative conditions includin...
BioInvent Recruits Michael Oredsson as New CEO
BioInvent International AB (STO: BINV) announces today that the Company's Board of Directors has appointed Michael Oredsson as new President and CEO. He will take office within six months. Michael Oredsson has a degree in International Business Administration and has for many years held senior executive positions in the pharmaceutical and biotech...
TSRI scientists devise new technique to find therapeutic antibodies
Scientists at The Scripps Research Institute have devised a powerful new technique for finding antibodies that have a desired biological effect. Antibodies, which can bind to billions of distinct targets, are already used in many of the world's best-...
Findings highlight importance of IL-21 in the development of antiviral vaccines
Scientists at Emory Vaccine Center have shown that an immune regulatory molecule called IL-21 is needed for long-lasting antibody responses in mice against viral infections.
Novel multiplex immunoassay approach to capture HIV antibodies
Detection of HIV antibodies is used to diagnose HIV infection and monitor trials of experimental HIV/AIDS vaccines. New, more sensitive detection systems being developed use microspheres to capture HIV antibodies and can measure even small amounts of...
Autoantibodies may form basis of lupus diagnostic test
Scientists believe a new diagnostic test for lupus could be developed by looking for the presence of certain antibodies in the blood.Antibodies are proteins manufactured by the immune system to help identify and neutralise bacteria, viruses and other foreign objects. However, autoantibodies cause tissue damage, as they are directed against the person's own proteins.Systemic lupus erythematosus...
Low Population Immunity Predicted If New Bird Flu Virus H7N9 Escalates Into A Human Pandemic
The level of immunity to the recently circulating H7N9 influenza virus in an urban and rural population in Vietnam is very low, according to the first population level study to examine human immunity to the virus, which was previously only found in b...
Modulating the immune system to combat metastatic cancer
(Journal of Clinical Investigation) In this issue of the Journal of Clinical Investigation, researchers led by Ronald Levy at Stanford University found that regulatory T cells that infiltrate tumors express proteins that can be targeted with therapeu...
[ElsaLys Biotech] spins out of [Transgene], raises €2.1mm in Series A round
Immunotherapeutics company [Transgene SA] has spun out [ElsaLys Biotech], and participated in the monoclonal antibody firm’s €2.1mm ($2.7mm) Series A round, which also included Sofimac Partners.
Peregrine Pharmaceuticals, The Little Biotech With The Golden Goose Of Immunotherapy
By Chris Lacoursiere:The annual conference of The American Society of Clinical Oncology (ASCO) is currently less than a few days away, and what is the buzz for this year's conference? Immunotherapy is the buzz word for this year's conference. Bavituximab is a phosphatidylserine (PS) binding monoclonal antibody (MAB) produced by Peregrine Pharmaceuticals (PPHM), which appears to be "Th...
Six Investigators Awarded Lyme Research Alliance Grants
Lyme Research Alliance announced it will fund six promising studies to find a reliable diagnostic test and effective treatment options for Lyme and other tick-borne diseases. Stamford, CT (PRWEB) May 23, 2013 Six innovative research projects have been awarded grants worth half a million dollars by Lyme Research Alliance, the nation's largest private nonprofit funder of Lyme dis...
Macrocyclics to Collaborate with Roche on Molecular Innovation for Nuclear Medicine
DALLAS, May 23, 2013 /PRNewswire/ -- After the successful completion of their first 2012 collaboration, Macrocyclics (an AREVA Med company) announced today a new collaborative research agreement with Roche for the continued development of novel chelating agents designed specifically by Macrocyclics for Roche's applications. (Logo: http://photos.prnewswire.com/prnh/20130523/DA20136...
BioFront Technologies Receives Funding Through Florida Institute Seed Capital Accelerator Program
Company Based on Technology Developed at Florida State University The Institute for the Commercialization of Public Research (the Institute) announced today that it has finalized a funding agreement with BioFront Technologies, producers of diagnostic kits and reagents that detect viral and allergenic proteins for food safety and infectious disease mark...
Powerful new method IDs therapeutic antibodies
Scientists have devised a powerful new technique for finding antibodies that have a desired biological effect. The newly reported technique should greatly speed the process of discovering medicines, diagnostics and laboratory reagents.
Arsanis Nominates Preclinical Candidate for Staphylococcus aureus Program
Receives additional grant support to expand its infectious disease antibody pipeline Arsanis Biosciences GmbH, a biotechnology company developing anti-infective human monoclonal antibodies, achieved a major milestone by nominating the preclinical development candidates for its lead program, a monoclonal antibody cocktail to prevent and treat severe...
Research could lead to 'universal' flu vaccine
“Scientists create new flu vaccine that works against many different strains of the virus,” The Independent reports. This headline, and several others like it, is based on early stage research into the development of alternative flu vaccine technologies. While the results of this research are promising, they do not mean that a universal flu jab has been developed. The study used a new techniq...
Vaccine blackjack: IL-21 critical to fight against viral infections
(Medical Xpress)—Scientists at Emory Vaccine Center have shown that an immune regulatory molecule called IL-21 is needed for long-lasting antibody responses in mice against viral infections.
ATLANTA, May 23, 2013 /PRNewswire/ -- Inhibikase Therapeutics, Inc., an emerging leader in infectious disease treatments, announced today that it will present new results on its antiviral program to 'prevent' PML at an industry conference sponsored by the PML Consortium (composed of Pfizer, Bristol-Meyers Squibb, Roche and Biogen Idec). JC polyomavirus (JCV) is the causative agent of Pr...
BUSAN, South Korea, May 23, 2013 /PRNewswire/ -- Pusan National University Yangsan Hospital, in collaboration with SillaJen, Inc., a private biotherapeutics and contract research company focused on research and development of targeted biological products for cancer, announced today a publication reporting the induction of functional anti-cancer antibodies in patients treated with the oncolytic and...
Sunlight Can Wake Up the Latent Herpes Virus; polyDNA Surveys the Public Knowledge
polyDNA answers new questions on herpes, HSV, herpes virus, cold sores, etc. collected from the public in its May, 2013 survey. Rochester, NY (PRWEB) May 23, 2013 Sun exposure can reactivate the herpes virus. Research has shown that sun exposure in people infected with oral herpes (HSV-1), may cause a flare up, or outbreak of fever blisters and cold sores. In polyDNA’s recent survey, respondent...
Johns Hopkins researchers find possible trigger of rheumatoid arthritis
In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system make...