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Early observations indicated that the Earth’s Van Allen radiation belts could be separated into an inner zone dominated by high-energy protons and an outer zone dominated by high-energy electrons. Subsequent studies showed that electrons of moderat...
The active galaxy NGC 4151 has a crucial role as one of only two active galactic nuclei for which black hole mass measurements based on emission line reverberation mapping can be calibrated against other dynamical techniques. Unfortunately, effectiv...
Evidence is mounting that the immense diversity of microorganisms and animals that live belowground contributes significantly to shaping aboveground biodiversity and the functioning of terrestrial ecosystems. Our understanding of how this belowground...
During immune-cell development, potentially self-reactive T cells are eliminated. It emerges that recruitment of a co-receptor bound to the T-cell receptor by the enzyme Lck is the rate-limiting step in this negative selection.
A geometric measurement of the distance to a nearby galaxy implies a larger mass for its central black hole than previously calculated, and a consequent increase for most other masses of such black holes. See Letter p.528
Five papers extend the list of cancers that respond to therapies that restore antitumour immunity by blocking the PD-1 pathway, and characterize those patients who respond best. See Letters p.558, p.563, p.568, p.572 & p.577
A study of the El Niño phenomenon over the past 21,000 years suggests that El Niño responded in complex ways to a changing climate, with several competing factors playing a part in its varying strength. See Letter p.550
In the study of haemophilia, man really does have a best friend.
The hunt is on for ways to diagnose and treat the joint problems that are now the main chronic problem in haemophilia.
A promising therapy curtails clotting inhibitors rather than replacing proteins that promote blood clotting.
Pills made from lettuce leaves could help to prevent one of the most serious complications of haemophilia treatment.
History explains why people with haemophilia, and their physicians, are cautious to believe that a cure is in sight, says Stephen Pemberton.
Extending the life of clotting factors may improve quality of life for people with haemophilia.
Repairing the faulty genes that cause haemophilia could ultimately cure the disease, but it will be a tough challenge.
People with the inherited bleeding disorder haemophilia lack factors that cause the blood to clot. The disease affects thousands of people around the world and has even played a part in historic events. By Neil Savage.
A distant memory.
The field of materials science is working to broaden the range of people it attracts.
The Rosetta spacecraft's Philae probe, which landed successfully on an orbiting comet on 12 November (see Naturehttp://doi.org/w8k; 2014), could be renamed Pheidippides — for its record-setting marathon run and transmission of its message before co...
We agree with Jie Zhang that university reform is needed to improve the quality of Chinese research papers (Nature514, 295–296;10.1038/514295a2014). A home-grown scientist in China might then stand a chance of winning a Nobel prize for
Jie Zhang rightly points out that China's universities need high-quality faculty members if they are to be competitive internationally (Nature514, 295–296,10.1038/514295a2014). But there are risks in giving individual colleges and departments more ...
Eminent scholars from around the world last month signed a statement on the 'brain training' industry (see go.nature.com/d2bpuj). They point out discrepancies between current scientific understanding of cognitive enhancement and advertising claims fo...
Without including social, cultural and behavioural responses to the Ebola epidemic, models may overestimate outbreak size (Nature515, 18;10.1038/515018a2014).Behavioural response, triggered by an epidemic, can slow down or even stop virus transmissio...
Your assertion that models of the Ebola epidemic have failed to project its course misrepresents their aims (see Nature515, 18;10.1038/515018a2014). They helped to inspire and inform the strong international response that may at last be slowing the e...
Richard Van Noorden considers a technical lecture that ultimately fails as theatre.