Latest Biotechnology, Pharmaceutical and Healthcare News - Page: 2 from Nature Publishing

03:27 EDT 16th September 2014 | BioPortfolio

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Showing News Articles 26–50 of 24,000+ from Nature Publishing

Monday 15th September 2014

Direct generation of three-photon polarization entanglement

A three-photon entangled Greenberger–Horne–Zeilinger state is directly produced by cascading two entangled down-conversion processes. Experimentally, 11.1 triplets per minute are detected on average. The three-photon entangled state is used for s...

Mid-infrared supercontinuum covering the 1.4–13.3 μm molecular fingerprint region using ultra-high NA chalcogenide step-index fibre

Mid-infrared supercontinuum generation with a record-breaking spectral coverage of 1.4–13.3 µm is demonstrated by launching intense ultra-short pulses into short pieces of ultra-high numerical aperture step-index chalcogenide glass optical fibre...

Quantum teleportation on a photonic chip

Teleportation of a photonic qubit is demonstrated on a reconfigurable photonic chip. All of the key elements of the teleportation protocol are performed. The average fidelity for the three linearly independent quantum states is higher than the classi...

High photon flux table-top coherent extreme-ultraviolet source

High photon flux with up to 1012 photons in the 25–40 eV range has been achieved in a new table-top coherent extreme ultraviolet (EUV) source based on phase-matched high-harmonic generation using a fibre laser. Intense and compact EUV sources are...

Sunday 14th September 2014

Histone H2A.Z subunit exchange controls consolidation of recent and remote memory

Memory formation is a multi-stage process that initially requires cellular consolidation in the hippocampus, after which memories are downloaded to the cortex for maintenance, in a process termed systems consolidation. Epigenetic mechanisms regulate ...

Discovery and characterization of small molecules that target the GTPase Ral

The Ras-like GTPases RalA and RalB are important drivers of tumour growth and metastasis. Chemicals that block Ral function would be valuable as research tools and for cancer therapeutics. Here we used protein structure analysis and virtual screening...

A Hox regulatory network of hindbrain segmentation is conserved to the base of vertebrates

A defining feature governing head patterning of jawed vertebrates is a highly conserved gene regulatory network that integrates hindbrain segmentation with segmentally restricted domains of Hox gene expression. Although non-vertebrate chordates displ...

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

Curli are functional amyloid fibres that constitute the major protein component of the extracellular matrix in pellicle biofilms formed by Bacteroidetes and Proteobacteria (predominantly of the α and γ classes). They provide a fitness advantage in ...

Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state

The reprogramming of epigenetic states in gametes and embryos is essential for correct development in plants and mammals. In plants, the germ line arises from somatic tissues of the flower, necessitating the erasure of chromatin modifications that ha...

Large, non-saturating magnetoresistance in WTe2

Magnetoresistance is the change in a material’s electrical resistance in response to an applied magnetic field. Materials with large magnetoresistance have found use as magnetic sensors, in magnetic memory, and in hard drives at room temperature, a...

Asian monsoons in a late Eocene greenhouse world

Asian monsoons were strongly active 40 million years ago and were enhanced by high atmospheric CO2 content. They were significantly weakened when CO2 levels decreased 34 million years ago and then reinitiated several million years later.

De novo assembly of soybean wild relatives for pan-genome analysis of diversity and agronomic traits

Sequencing and de novo assembly of seven wild relatives of soybean yields insights relevant to crop domestication and improvement.

Global analysis of protein structural changes in complex proteomes

Coupling limited proteolysis and a proteomics workflow enables measurement of both subtle and wholesale protein conformational changes in a eukaryotic proteome.

Atomic structure and dynamic behaviour of truly one-dimensional ionic chains inside carbon nanotubes

Successful synthesis of stable one-dimensional ionic crystals composed of two atomic species and encapsulated in carbon nanotubes is now demonstrated.

Two-step nucleation mechanism in solid–solid phase transitions

Single-particle-resolution video microscopy of films of colloidal particles shows that solid–solid transitions between square and triangular lattices occur through a two-step nucleation mechanism that involves liquid nuclei.

Current-induced transition from particle-by-particle to concurrent intercalation in phase-separating battery electrodes

Investigation of the individual state-of-charge of particles in the phase-separating battery electrode lithium iron phosphate reveals that the fraction of active particles is highly dependent on cycle rate and direction. The findings could lead to en...

Digital metamaterials

Inspired by Boolean binary algebra, an approach to design electromagnetic metamaterials with desired permittivity by using just two elemental building blocks is demonstrated analytically and numerically.

Saturday 13th September 2014

Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma

Modeling complexity in pathologist workload measurement: the Automatable Activity-Based Approach to Complexity Unit Scoring (AABACUS)

A clinicopathological and molecular analysis of 200 traditional serrated adenomas

MYD88 L265P mutation analysis helps define nodal lymphoplasmacytic lymphoma

Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist

Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas

Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas

CD117 expression in breast phyllodes tumors correlates with adverse pathologic parameters and reduced survival


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