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11:26 EST 21st November 2014 | BioPortfolio

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Showing News Articles 26–50 of 26,000+ from Nature Publishing

Thursday 20th November 2014

Reply to Comment on: ‘Possible pro-carcinogenic association of endotoxin on lung cancer among Shanghai women textile workers’

Comment on ‘Possible pro-carcinogenic association of endotoxin on lung cancer among Shanghai women textile workers’

Response to: Comment on 'Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay'

Comment on ‘Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay’: premature all-clear for nuclear power

MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1

Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer

Unlocking the potential of retinoic acid in anticancer therapy

Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs

Activation of the JAK/STAT pathway in Behcet’s disease

An enteric virus can replace the beneficial function of commensal bacteria

Intestinal microbial communities have profound effects on host physiology. Whereas the symbiotic contribution of commensal bacteria is well established, the role of eukaryotic viruses that are present in the gastrointestinal tract under homeostatic c...

Business culture and dishonesty in the banking industry

Trust in others’ honesty is a key component of the long-term performance of firms, industries, and even whole countries. However, in recent years, numerous scandals involving fraud have undermined confidence in the financial industry. Contemporary ...

Design and fabrication of memory devices based on nanoscale polyoxometalate clusters

Flash memory devices—that is, non-volatile computer storage media that can be electrically erased and reprogrammed—are vital for portable electronics, but the scaling down of metal–oxide–semiconductor (MOS) flash memory to sizes of below ten ...

RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation

Specialized ribosomes (with a particular protein composition) carry out translation of specific transcripts; analysis of Hox mRNA translation in mice reveals that unique RNA structural elements within their 5′ UTRs, including internal ribosome entr...

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

Atomic resolution crystal structures of influenza A and B polymerases are presented; comparison of these structures provides mechanistic insight into influenza polymerase functions, explaining the processes of cap-snatching and cap-dependent priming,...

Structure of influenza A polymerase bound to the viral RNA promoter

The crystal structure of the bat-specific influenza A polymerase in complex with the viral RNA promoter is presented, revealing how binding of the 5′ end of the viral RNA is required to activate or enhance the polymerase allosterically.

Microbiology: A backup for bacteria

The finding that intestinal viruses can substitute for intestinal bacteria to promote the health of their mammalian hosts raises the possibility that viruses in the gut may be beneficial in some circumstances.

Behavioural economics: Professional identity can increase dishonesty

An experiment shows that although bank employees behave honestly on average, their dishonesty increases when they make decisions after having been primed to think about their professional identity.

Diabetes: The good in fat

A new class of fatty acid — found in food and synthesized by mammalian tissues — enhances glucose uptake from the blood and reduces inflammation, suggesting that these fats might be used to treat diabetes.

Molecular biology: Entry signals control development

Certain structural elements allow messenger RNAs not usually processed by the protein-synthesis apparatus to be translated. It now seems that they also control the expression of genes involved in embryonic development.

Topologically associating domains are stable units of replication-timing regulation

Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program. In mammals, replication timing is cell-type-specific with at least half the genome switching replication timing during development, primarily in units of 40...

Direct human influence on atmospheric CO2 seasonality from increased cropland productivity

Ground- and aircraft-based measurements show that the seasonal amplitude of Northern Hemisphere atmospheric carbon dioxide (CO2) concentrations has increased by as much as 50 per cent over the past 50 years. This increase has been linked to changes i...

Agricultural Green Revolution as a driver of increasing atmospheric CO2 seasonal amplitude

The atmospheric carbon dioxide (CO2) record displays a prominent seasonal cycle that arises mainly from changes in vegetation growth and the corresponding CO2 uptake during the boreal spring and summer growing seasons and CO2 release during the autum...

Artificial chemical and magnetic structure at the domain walls of an epitaxial oxide

Progress in nanotechnology requires new approaches to materials synthesis that make it possible to control material functionality down to the smallest scales. An objective of materials research is to achieve enhanced control over the physical propert...

The power of relativistic jets is larger than the luminosity of their accretion disks

Theoretical models for the production of relativistic jets from active galactic nuclei predict that jet power arises from the spin and mass of the central supermassive black hole, as well as from the magnetic field near the event horizon. The physica...

Principles of regulatory information conservation between mouse and human

To broaden our understanding of the evolution of gene regulation mechanisms, we generated occupancy profiles for 34 orthologous transcription factors (TFs) in human–mouse erythroid progenitor, lymphoblast and embryonic stem-cell lines. By combining...

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