Latest Biotechnology, Pharmaceutical and Healthcare News - Page: 5
Showing News Articles 101–125 of 16,000+
To the Editor: The Viewpoint on distracted driving by Drs Coben and Zhu missed the mark on the issues of potential effectiveness of legislation and benefits of hands-free phone interfaces. Coben and Zhu stated that “legislation that cannot be strin...
The Health Checkup Was It Ever Effective? Could It Be Effective?
In this issue of JAMA, the JAMA Clinical Evidence Synopsis by Krogsbøll et al summarizes a systematic review of 9 randomized trials of a general health check. A general health check is defined as health care motivated by the need to assess general h...
The Evolution of Type 1 Diabetes The Evolution of Type 1 Diabetes
Type 1 diabetes (T1D) occurs in individuals with a genetic predisposition to the disease, predominantly from a human leukocyte antigen (HLA)-related immunogenotype that accounts for approximately 60% of the genetic influence. In these individuals who...
The outbreak of invasive fungal infections among patients who received injections of contaminated methylprednisolone acetate from the New England Compounding Center continues.
Clinical QuestionWhat are the benefits and harms of general health checks for adult populations?Bottom LineCompared with usual care, offers of health checks were not associated with lower rates of all-cause mortality, mortality from cardiovascular di...
ImportanceRandomized clinical trials suggest the benefit of intravenous tissue-type plasminogen activator (tPA) in acute ischemic stroke is time dependent. However, modest sample sizes have limited characterization of the extent to which onset to tre...
ImportanceType 1 diabetes usually has a preclinical phase identified by circulating islet autoantibodies, but the rate of progression to diabetes after seroconversion to islet autoantibodies is uncertain.ObjectiveTo determine the rate of progression...
ImportanceInjection of contaminated methylprednisolone has resulted in an unprecedented nationwide outbreak of Exserohilum rostratum fungal infections, manifested initially as meningitis and/or basilar stroke. Insidious onset of spinal or paraspinal...
ImportanceTissue verification of noncaseating granulomas is recommended for the diagnosis of sarcoidosis. Bronchoscopy with transbronchial lung biopsies, the current diagnostic standard, has moderate sensitivity in assessing granulomas. Endosonograph...
ImportanceThe immunogenicity and the effects of live attenuated measles-mumps-rubella (MMR) vaccination on disease activity in patients with juvenile idiopathic arthritis (JIA) are matters of concern, especially in patients treated with immunocomprom...
The Boston Marathon Response Why Did It Work So Well?
On Monday, April 15, 2013, Boston emergency medical services and other agencies transported scores of casualties to local hospitals within 90 minutes of the 2 explosions at 2:50 PM near the Boylston Street finish line of the 117th Boston Marathon. Br...
Spinal Injection Therapy for Low Back Pain Spinal Injection Therapy for Low Back Pain
Low back pain is commonly reported by patients in primary care and will affect most adults at some time during their lifetime. The socioeconomic burden of low back pain is high. In the United States, the condition accounts for 2% of all physician off...
The national emphasis on reducing preterm birth, and the increase in scheduled deliveries, has created confusion around the definition of term gestation. The concept of “term” gestation provides guidance to clinicians and influences the public's...
To improve health care in the United States, the Institute of Medicine (IOM) has advanced the “learning health care system”—a place where “each patient-care experience naturally reflects the best available evidence, and, in turn, adds seamles...
Co prescription of statins and antibiotics linked to extra deaths
Ann Intern Med2013;158:869-76Evidence is growing of an important drug interaction between widely used statins and antibiotics. Clarithromycin and erythromycin inhibit the cytochrome P450 isoenzyme...
Domestic violence is common among women in fracture clinics
Lancet2013; doi:10.1016/S0140-6736(13)61205-2Women attending fracture clinics report a high prevalence of domestic violence. In the latest survey from clinics on three continents, one in six women...
Inhaled adrenaline no better than inhaled saline for babies with bronchiolitis
N Engl J Med2013;368:2286-93A new trial challenges a widespread treatment for infants with bronchiolitis. Inhalations of racemic adrenaline worked no better than inhalations of saline in infants...
Conventional triple therapy as good as etanercept for uncontrolled rheumatoid arthritis
N Engl J Med2013; doi:10.1056/NEJMoa1303006bmj;346/jun18_8/f3846/FIG1F1fig1When methotrexate fails to control rheumatoid arthritis, patients can add other disease modifying drugs or opt for more...
Lives lost with every 15 minute delay in thrombolysis after acute stroke
JAMA2013;309:2480-8Adults with acute ischaemic stroke need thrombolysis within 4.5 hours, but even within that time frame those treated sooner do significantly better than those treated later,...
Tenofovir helps prevent HIV in drug users
Lancet 2013; doi:10.1016/S0140-6736(13)61127-7A team of researchers from Thailand and the US has shown for the first time that tenofovir can help prevent HIV in injecting drug users. Daily...
Background: A promising way in diagnostic and therapeutic applications is the development of peptide amphiphiles (PAs). Peptides with a palmitic acid alkylchain were designed and characterized to study the effect of the structure modifications on sel...
Patients Lead The Way As Medicine Grapples With Apps
Christine Porter is hooked on the My Fitness Pal app. In October, after deciding to lose 50 pounds, Porter started typing in everything she eats, drinks and any exercise she gets. “This is like my main page here,” says Porter, who lost 42 pounds in nine months. “It’s telling me I have about 1,200 calories remaining for the day. When I want to record something I just click t...
UK regulators deny claims that their access to oseltamivir trial data was insufficient
The main regulators of drugs in the United Kingdom have denied that they had insufficient access to clinical trial data on the antiviral oseltamivir from its manufacturer, despite concerns about...
Dutch doctors get guidance on care of terminally ill newborn babies
The Royal Dutch Medical Association has published professional standards to try to clarify the line between palliative care of terminally ill newborn babies and deliberately killing them.Driving the...
