Latest "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" News Stories

10:07 EDT 26th July 2016 | BioPortfolio

Here are the most relevant search results for "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" found in our extensive news archives from over 250 global news sources.

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Showing "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" News Articles 1–25 of 3,400+

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Sustained release of rhBMP-2 from microporous tricalciumphosphate using hydrogels as a carrier

Tissue engineering and bone substitutes are subjects of intensive ongoing research. If the healing of bone fractures is delayed, osteoinductive materials that induce mesenchymal stem cells (MSCs) to form bone ...

IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis

Interleukin-17A (IL-17A) plays a pathogenic role in several rheumatic diseases including spondyloarthritis and, paradoxically, has been described to both promote and protect from bone formation. We therefore e...

Protein combination improves bone regeneration, UCLA study shows

(University of California - Los Angeles) UCLA researchers have found a combination of proteins that could improve clinical bone restoration; and could lead towards the development of therapeutic treatments for skeletal defects, bone loss and osteoporosis. They found that the combination of two proteins, NELL-1 and BMP2, increased bone formation while inhibiting the formation of fat cells. By contr...

Study identifies a key to bone formation, vertebrate evolution

Researchers have identified a key action of a watershed gene critical to bone formation and the evolution of vertebrates. The Sp7 or Osterix gene more than likely emerged from an ancestral gene family about 400 million years ago, expanding the diversity of life and programming the development of bone-secreting osteoblast cells. The closest living relatives to vertebrates, including sea squirts and...

Forteo stimulates bone formation within femoral neck after total hip replacement

Forteo promotes rapid bone formation in the femoral neck, with pronounced effects in cancellous and endocortical bone envelopes, according to recent findings. Felicia Cosman, MD, an endocrinologist at Helen Hayes Hospital Regional Bone Center in West Haverstraw, New York, and colleagues evaluated 25 women (mean age, 71.5 years) and 15 men (mean age, 68.9 years) to determine the effect of For...

New protein combination 'could aid future treatment of bone conditions'

The treatment of skeletal defects, bone loss and osteoporosis could be facilitated by the recent discovery of a promising new protein combination.US researchers at the University of California, Los Angeles (UCLA) have discovered that a combination of two proteins - NELL-1 and BMP2 - has the ability to increase bone formation more safely and effectively than is currently possible.BMP2 is already em...

Bone marrow contribution to synovial hyperplasia following joint surface injury

Joint surface injury, a known risk factor for osteoarthritis, triggers synovial hyperplasia, which involves proliferation of mesenchymal stromal/stem cells (MSCs). Whether these proliferative MSCs are resident...

Study identifies a key to bone formation and vertebrate evolution

Researchers in a USC-led study said they have identified a key action of a watershed gene critical to bone formation and the evolution of vertebrates.

Revolutionary Bone Graft Cement FDA & CE Approved: 4MATRIX

(PRWEB) April 25, 2016 Composed of pure biphasic calcium sulfate & hydroxyapatite and characterized by a predetermined setting time and resorption rate, 4MATRIX is the preferred augmentation product for a wide variety of dental bone grafting procedures. This all-in-one innovative produ...

New bone turnover measure is more accurate predictor of postmenopausal bone loss

A new measure of bone turnover—bone balance—that assesses bone breakdown and formation across the whole skeleton, based on urine and blood samples, is a more accurate predictor of bone loss in...


Revolutionary Bone Graft Cement FDA & CE Approved: 4MATRIX

Advanced composition, simplicity and ease of use: These terms best describe the new 4MATRIX Bone Graft solution delivered by MIS Implants Technologies Ltd. (PRWEB) April 25, 2016 Composed of pure biphasic calcium sulfate & hydroxyapatite and characterized by a predetermined setting time and resorption rate, 4MATRIX is the preferred augmentation product for a wide variety of dental bone grafti...

SI-BONE announces expansion of European operations with creation of SI-BONE UK

SI-BONE Inc. recently announced the expansion of its European operations with the formation of SI-BONE UK Ltd. In addition to the new European headquarters, SI-BONE announced two new management team members. Richard Moss joins the European management team as General Manager United Kingdom (U.K.) & Ireland, and Silvio Tarantino has been appointed finance director for Europe, the Middle East and Afr...

HIV-infected young males have higher rates of bone loss than females

(Children's Hospital Los Angeles) Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals -- assessed by sex and HI...

Drug candidate stops extra bone growth in animal model of rare, genetic disease

PHILADELPHIA - New preclinical research provides support to a drug that has been repurposed to possibly treat a rare and extremely disabling genetic bone disease, particularly in children. In that disease, fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, alters skeletal bone formation, and limits motion, breathing, and swallowing, among a host of progressive...

Romosozumab Tops Teriparatide in Phase 3 Osteoporosis Study

Romosozumab, a novel investigational agent that both promotes bone formation and inhibits bone resorption, showed positive results at the hip and spine at 1 year. Medscape Medical News

Nano-biomimetic artificial cornea set to move from proof-of-concept to preclinical trials.

Almost all living organisms are uniquely adapted to the environment in which they live, some so well that researchers investigate them with the view to replicating their natural designs in products and technologies for human-use. This process, called biomimetics or biomimicry, is the exciting arena where nature and engineering meet.  An example of this are cicadas and dragonflies whose wings

Medical Applications of Nano Magnetite

Medical Applications of Nano Magnetite Author: Danut Dragoi, PhD Nano magnetite refers to small crystals of Fe3O4 in nano-metric range that preserves some specific magnetic properties of the magnetite bulk crystal such as the magnetism at saturation, Curie temperature, coercive magnetic force, hysteresis loop, etc. A discussion of medical applications of nano-magnetic particles is shown […]

Biomimetic method produces large numbers of MRI-trackable mesenchymal stem cells.

Mesenchymal stem cells (MSCs) are among the major stem cells used for cell therapy and regenerative medicine. In-vivo cell-tracking by magnetic resonance imaging (MRI) is crucial for regenerative medicine, allowing verification that the transplanted cells reach the targeted sites.  However, the results from trials using stem cells have proved problematic due to varying results and inadequate trac...

Drug candidate halts crippling excess bone growth in animal model of a rare bone disease

New research in laboratory animals suggests that the drug palovarotene may prevent multiple skeletal problems caused by a rare but extremely disabling genetic bone disease, and may even be a candidate for use in newborn babies with the condition. Scientists at The Children's Hospital of Philadelphia, who previously repurposed the drug to prevent excess bone formation in animal models of fibrodyspl...

Hydrodynamic loading in concomitance with exogenous cytokine stimulation modulates differentiation of bovine mesenchymal stem cells towards osteochondral lineages

Mesenchymal stem cells (MSCs) are viewed as a having significant potential for tissue engineering and regenerative medicine therapies. Clinical implementation of MSCs, however, demands that their preparation b...

Structured light enables biomimetic swimming and versatile locomotion of photoresponsive soft microrobots

Soft biomimetic microswimmers and microrobots made of photoactive liquid-crystal elastomers and whose body shape is controlled by structured light are able to self-propel and perform complex motion patterns on demand.

Some patients exposed to rhBMP-2 may develop heterotopic bone after spinal fusion

ORLANDO, Fla. — During a 2.5-year period, nearly 3% of patients who underwent thoracic or lumbar spinal fusion developed formations of ectopic recombinant human bone morphogenic-2 bone that were not easily detectable on plain CT scans at 1 month to 3 months after the procedure, according to findings of a study presented at Spine Summit 2016: CNS/AANS Section on Disorders of the Spine & Periphera...

Bone: Does anti-sclerostin therapy promote inflammation in rheumatoid arthritis?

One of the most promising new approaches currently in clinical trials for postmenopausal osteoporosis is the promotion of bone formation by antibodies directed against the Wnt inhibitor, sclerostin. A new study by Wehmeyer and colleagues suggests that this approach might have a pro-inflammatory effect in patients with tumour necrosis factor (TNF)-dependent rheumatoid arthritis.

This amazing biomimetic anthropomorphic robotic hand contains 3D printed bones

 SOURCE Feb 18, 2016 | By Benedict Zhe Xu and Emanuel Todorov, engineers from the University of Washington, Seattle, have built a highly complex 3D printed robotic hand. The pair obtained a 3D scan of a cadaver skeleton in order to design 3D printed bones for the biomimetic device. To […]

High-load exercise may benefit long-term bone health

Compared with nonweight-bearing activities, such as cycling, running and other exercises that put greater strain on bones may help improve long-term bone health, according to study findings presented at the European Congress of Endocrinology in Munich. “Chronic large and repetitive loads — as in mountain ultramarathon, but also in running — modify bone metabolism by enhancing formation,” G...

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