Latest "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" News Stories

09:24 EST 22nd January 2017 | BioPortfolio

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Showing "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" News Articles 1–25 of 3,500+

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Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Mesenchymal stem cells (MSCs) actively contribute to the formation of the tumour microenvironment by producing various factors that affect tumour growth and response to therapy. Moreover, MSCs can modulate tumour immunity. This Review discusses the various roles of MSCs in cancer and highlights potential strategies to target pro-tumorigenic activities of MSCs or take advantage of the tumour-homing...

Green Bone: Biomimetic – Reabsorbable – Bamboo-derived bone graft scaffold

GREENBONE ORTHO SRL wants to become a worldwide leader for bone regeneration by providing innovative and easy to use bio-inspired solutions that will help cure severe diseases. The primary goal of GREENBONE is to develop a highly innovative bone implant, to generate biomimetic – reabsorbable – Bamboo-derived bone graft scaffold suitable to address non-union fractures and other very nasty skel...

Researchers propose mechanism for spread of metastatic breast cancer to bone

New research explains how metastatic breast cancer cells might use bone marrow-derived mesenchymal stem cells (MSCs) to help them spread to bone tissue. A study using a 3D scaffold model has shown that breast tumor-derived factors can promote the maturation of MSCs into bone cells, and that mechanical compression of the scaffold further stimulates bone development, according to an article publishe...

Injected mix of bone-augmenting agents causes new bone growth in mouse jaws

(Tokyo Medical and Dental University) A Tokyo Medical and Dental University(TMDU)-centered research team combined a protein that stimulates bone formation with a peptide that promotes osteoblast differentiation, and delivered them into mouse jawbones by injection within a gelatin carrier. The technique induced formation of new bone, suggesting its potential as a non-invasive means of replacing los...

Self-assembly of nanoparticles into biomimetic capsid-like nanoshells

Biomolecular nanoscale compartments are ubiquitous in living systems. Although their formation is fairly straightforward, the same cannot be said of their inorganic counterparts. In this study, uniform nanoshells are observed self-assembling from stabilizer-free inorganic nanoparticles in water, under ambient conditions, without the need for spherical tiling. This enables further study of inorgani...

Results From Phase 3 BRIDGE Study Show Romosozumab Significantly Increases Bone Mineral Density ...

"Romosozumab has the ability to improve bone mass, structure and strength by both increasing bone formation and decreasing bone resorption," said E. Michael Lewiecki, Read more...

Biomaterials: 'Bones' made with 3D printer

Synthetic bones promote natural bone regeneration after being implanted into animals.Ramille Shah at Northwestern University in Evanston, Illinois, and her colleagues used a 3D printer to generate 'hyperelastic bone'. The main component of the material was hydroxyapatite — a calcium mineral similar to one

Researchers shed light on repair mechanism for severe corneal injuries

In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs)—which can differentiate into a variety of cells, including bone, cartilage, muscle and fat cells—are capable of returning clarity to scarred corneas; however, the mech...


Bone: Antiplatelet agent promotes bone formation

Research reveals how novel osteoporosis drug increases bone mass

(Wiley) Abaloparatide, a selective activator of the parathyroid hormone receptor, has recently been shown to reduce fractures in postmenopausal women with osteoporosis. Now new research shows that abaloparatide increases bone mass in rats whose ovaries have been removed by stimulating bone formation, without effects on bone resorption.

Bone-forming growth factor – Osteolectin – may one day reverse osteoporosis – new discovery

A bone-forming growth factor that reverses osteoporosis in mice has been found by scientists, they report in eLife. We already knew that Osteolectin is made by certain bone marrow and bone cells, but now researchers from the US have found that it promotes the formation of new bone from skeletal stem cells in the bone […] The post Bone-forming growth factor – Osteolectin – may one...

The Fourth State of Matter, Plasma: A Technology to Improve Bone Healing?

Tuning cold plasma can either promote or inhibit bone formation

Study Shows Unmodified Stem Cells Might Stop Osteoporosis Caused by Autoimmune Drugs

An infusion of a healthy donor’s unmodified stem cells might one day be used to prevent a type of osteoporosis caused by glucocorticoid therapy, according to a study published this month in STEM CELLS Translational Medicine. Durham, NC (PRWEB) August 18, 2016 An infusion of a healthy donor’s unmodified stem cells might one day be used to prevent a type of osteoporosis caused by glucocorticoid...

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure.

Serum Bone Alkaline Phosphatase Activity Methods Compared

Serum bone alkaline phosphatase is a marker of bone formation and metabolism, however, existing methods for measuring it have their...

VIDEO: Decades of research point to therapies to discourage bone aging

ATLANTA — In this video exclusive, Sundeep Khosla, MD, professor of medicine and physiology at Mayo Clinic in Rochester, Minnesota, discusses his work involving sex steroids, coupling and age-related bone loss over 3 decades and offers some clinical implications of the findings.Beginning in the late 1980s, Khosla and colleagues explored the roles of testosterone and estrogen on bone formation an...

Breakthrough for bone regeneration via double-cell-layered tissue engineering technique

Various technologies have been developed to introduce laboratory-grown bone-forming cells into bone defects to promote their repair. However, these have many limitations as the conditions of the cells and their surroundings do not accurately mimic those typically found in the body. This means they cannot optimally promote bone formation. A research team at Tokyo Medical and Dental University (TMDU...

Could suppression of Gαq/11 signaling be a promising target for treating bone loss?

Intermittent parathyroid hormone treatment (iPTH) and mechanical loading through exercise have both been shown to stimulate bone formation. These osteoanabolic stimuli are partially mediated by G protein-coupled receptors. Previous studies have suggested that enhanced signalling through the Gαq/11 pathway inhibits the bone-building actions of PTH, however the influence of enhanced Gαq/11...

Extrusion for unilamellar liposome formation

Why you should chose extrusion for your liposomal enhancement.

UC Berkeley research spurs hope for those with bone deformities

UC BERKELEY/COURTESY SOURCE October 2016 Creating hope for those with bone deformities, UC Berkeley professor Michael Rape and his laboratory team discovered a link between stem cell and calcium development in bone formation and growth in findings published Thursday in the journal Cell. With help from Nobel Prize-winning UC Berkeley professor Randy […]

Bone-coupling researcher receives ASBMR achievement award

Merry Jo Oursler, PhD, professor of medicine in the department of endocrinology, diabetes, metabolism and nutrition at the Mayo Clinic in Rochester, Minnesota, received the Paula Stern Achievement Award from the American Society for Bone and Mineral Research, which recognizes women in bone research who have made significant scientific achievements and who have promoted the professional development...

Ras signaling regulates osteoprogenitor cell proliferation and bone formation

Fully Functional 'Nano-Snowman' Has Applications for Providing Greener Energy

NewsScientists have captured the formation of a platinum encrusted nanoparticle that bears a striking resemblance to a festive snowman.

Tiny robot 'nano-fish' may one day deliver drugs inside the body

(—A combined team of researchers from the Harbin Institute of Technology in China and the University of California in the U.S. has developed a nano-sized, remotely controlled fish that is able to swim in liquids when a magnetic field is applied. The team has published the details of their research in the journal Nano Small Micro.

Scientists find that mechanical behavior of tiny structures is affected by atomic defects

An international team of scientists with participation from the University of Göttingen, the Indian Institute of Science, Bangalore, Pennsylvania State University, and Wright State University has measured the mechanics of tiny crystalline ceramics. Materials are made of atoms, and if they are arranged periodically, they are called crystalline structures. If the size of these crystalline structure...

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