Latest "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" News Stories

16:39 EDT 27th October 2016 | BioPortfolio

Here are the most relevant search results for "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" found in our extensive news archives from over 250 global news sources.

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Showing "Enhancement bone formation transduced MSCs biomimetic nano hydroxyapatite" News Articles 1–25 of 3,300+

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New drug candidate could treat both type 2 diabetes, bone loss

A new study has shown that a new class of drug candidates increases bone mass by expanding bone formation (deposition of new bone) and bone turnover (a normal process of replacement of old bone).

Sustained release of rhBMP-2 from microporous tricalciumphosphate using hydrogels as a carrier

Tissue engineering and bone substitutes are subjects of intensive ongoing research. If the healing of bone fractures is delayed, osteoinductive materials that induce mesenchymal stem cells (MSCs) to form bone ...

IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis

Interleukin-17A (IL-17A) plays a pathogenic role in several rheumatic diseases including spondyloarthritis and, paradoxically, has been described to both promote and protect from bone formation. We therefore e...

Study identifies a key to bone formation, vertebrate evolution

Researchers have identified a key action of a watershed gene critical to bone formation and the evolution of vertebrates. The Sp7 or Osterix gene more than likely emerged from an ancestral gene family about 400 million years ago, expanding the diversity of life and programming the development of bone-secreting osteoblast cells. The closest living relatives to vertebrates, including sea squirts and...

Injected mix of bone-augmenting agents causes new bone growth in mouse jaws

(Tokyo Medical and Dental University) A Tokyo Medical and Dental University(TMDU)-centered research team combined a protein that stimulates bone formation with a peptide that promotes osteoblast differentiation, and delivered them into mouse jawbones by injection within a gelatin carrier. The technique induced formation of new bone, suggesting its potential as a non-invasive means of replacing los...

Study identifies a key to bone formation and vertebrate evolution

Researchers in a USC-led study said they have identified a key action of a watershed gene critical to bone formation and the evolution of vertebrates.

Biomaterials: 'Bones' made with 3D printer

Synthetic bones promote natural bone regeneration after being implanted into animals.Ramille Shah at Northwestern University in Evanston, Illinois, and her colleagues used a 3D printer to generate 'hyperelastic bone'. The main component of the material was hydroxyapatite — a calcium mineral similar to one

Bone marrow contribution to synovial hyperplasia following joint surface injury

Joint surface injury, a known risk factor for osteoarthritis, triggers synovial hyperplasia, which involves proliferation of mesenchymal stromal/stem cells (MSCs). Whether these proliferative MSCs are resident...

New bone turnover measure is more accurate predictor of postmenopausal bone loss

A new measure of bone turnover—bone balance—that assesses bone breakdown and formation across the whole skeleton, based on urine and blood samples, is a more accurate predictor of bone loss in...


Researchers shed light on repair mechanism for severe corneal injuries

In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs)—which can differentiate into a variety of cells, including bone, cartilage, muscle and fat cells—are capable of returning clarity to scarred corneas; however, the mech...

Bone: Antiplatelet agent promotes bone formation

Research reveals how novel osteoporosis drug increases bone mass

(Wiley) Abaloparatide, a selective activator of the parathyroid hormone receptor, has recently been shown to reduce fractures in postmenopausal women with osteoporosis. Now new research shows that abaloparatide increases bone mass in rats whose ovaries have been removed by stimulating bone formation, without effects on bone resorption.

Researchers employ novel approach to assemble peptoids on a solid surface

Nature exquisitely assembles proteins and peptides into highly ordered functional materials, such as those critical for bone formation. These natural materials inspire researchers to innovate approaches to mimic nature for a range of potential biomedical applications. Recently Pacific Northwest National Laboratory (PNNL) -led materials scientists assembled networks of highly ordered synthetic prot...

The Fourth State of Matter, Plasma: A Technology to Improve Bone Healing?

Tuning cold plasma can either promote or inhibit bone formation

Study Shows Unmodified Stem Cells Might Stop Osteoporosis Caused by Autoimmune Drugs

An infusion of a healthy donor’s unmodified stem cells might one day be used to prevent a type of osteoporosis caused by glucocorticoid therapy, according to a study published this month in STEM CELLS Translational Medicine. Durham, NC (PRWEB) August 18, 2016 An infusion of a healthy donor’s unmodified stem cells might one day be used to prevent a type of osteoporosis caused by glucocorticoid...

Serum Bone Alkaline Phosphatase Activity Methods Compared

Serum bone alkaline phosphatase is a marker of bone formation and metabolism, however, existing methods for measuring it have their...

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure.

VIDEO: Decades of research point to therapies to discourage bone aging

ATLANTA — In this video exclusive, Sundeep Khosla, MD, professor of medicine and physiology at Mayo Clinic in Rochester, Minnesota, discusses his work involving sex steroids, coupling and age-related bone loss over 3 decades and offers some clinical implications of the findings.Beginning in the late 1980s, Khosla and colleagues explored the roles of testosterone and estrogen on bone formation an...

Breakthrough for bone regeneration via double-cell-layered tissue engineering technique

Various technologies have been developed to introduce laboratory-grown bone-forming cells into bone defects to promote their repair. However, these have many limitations as the conditions of the cells and their surroundings do not accurately mimic those typically found in the body. This means they cannot optimally promote bone formation. A research team at Tokyo Medical and Dental University (TMDU...

Could suppression of Gαq/11 signaling be a promising target for treating bone loss?

Intermittent parathyroid hormone treatment (iPTH) and mechanical loading through exercise have both been shown to stimulate bone formation. These osteoanabolic stimuli are partially mediated by G protein-coupled receptors. Previous studies have suggested that enhanced signalling through the Gαq/11 pathway inhibits the bone-building actions of PTH, however the influence of enhanced Gαq/11...

UC Berkeley research spurs hope for those with bone deformities

UC BERKELEY/COURTESY SOURCE October 2016 Creating hope for those with bone deformities, UC Berkeley professor Michael Rape and his laboratory team discovered a link between stem cell and calcium development in bone formation and growth in findings published Thursday in the journal Cell. With help from Nobel Prize-winning UC Berkeley professor Randy […]

Bone-coupling researcher receives ASBMR achievement award

Merry Jo Oursler, PhD, professor of medicine in the department of endocrinology, diabetes, metabolism and nutrition at the Mayo Clinic in Rochester, Minnesota, received the Paula Stern Achievement Award from the American Society for Bone and Mineral Research, which recognizes women in bone research who have made significant scientific achievements and who have promoted the professional development...

Ras signaling regulates osteoprogenitor cell proliferation and bone formation

Biomimetic method produces large numbers of MRI-trackable mesenchymal stem cells.

Mesenchymal stem cells (MSCs) are among the major stem cells used for cell therapy and regenerative medicine. In-vivo cell-tracking by magnetic resonance imaging (MRI) is crucial for regenerative medicine, allowing verification that the transplanted cells reach the targeted sites.  However, the results from trials using stem cells have proved problematic due to varying results and inadequate trac...

Bone: Does anti-sclerostin therapy promote inflammation in rheumatoid arthritis?

One of the most promising new approaches currently in clinical trials for postmenopausal osteoporosis is the promotion of bone formation by antibodies directed against the Wnt inhibitor, sclerostin. A new study by Wehmeyer and colleagues suggests that this approach might have a pro-inflammatory effect in patients with tumour necrosis factor (TNF)-dependent rheumatoid arthritis.

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