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USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

15:35 EDT 29 Jun 2012 | Nature Publishing

Ten Dijke and colleagues identify USP4 as a deubiquitylating enzyme (DUB) for the TGF-β receptor I in a screen for ubiquitin-specific proteases affecting TGF-β signalling. USP4, present in a complex with other DUBs, is regulated by AKT-mediated p..

Original Article: USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

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