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SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

16:20 EDT 8 Jul 2012 | Nature Publishing

The molecular determinants of malignant cell behaviours in breast cancer remain only partially understood. Here we show that SHARP1 (also known as BHLHE41 or DEC2) is a crucial regulator of the invasive and metastatic phenotype in triple-negative bre..

Original Article: SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

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