[Comment] The coming of age of MEK
22:05 EDT 15 Jul 2012 | The Lancet
An important pathway in oncology is the MAPK signal cascade, incorporating the enzymes RAS, RAF, MEK, and ERK. After the discovery that genes encoding RAS and the RAF isoform BRAF were oncogenic, much effort has been made to target this pathway, to p..
Original Article: [Comment] The coming of age of MEK
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