ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres
12:30 EDT 28 Jul 2012 | Nature Publishing
Telomere deprotection, despite triggering the same DNA damage response machinery as ionizing radiation, arrests the mammalian cell cycle via a distinct mechanism involving CDC25C phosphatase regulation.
Original Article: ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres
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