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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

17:24 EDT 29 Jul 2012 | Nature Publishing

The jumonji (JMJ) family of histone demethylases are Fe2+- and α-ketoglutarate-dependent oxygenases that are essential components of regulatory transcriptional chromatin complexes. These enzymes demethylate lysine residues in histones in a methylati..

Original Article: A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

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