A mouse model to identify cooperating signaling pathways in cancer
14:49 EDT 6 Aug 2012 | Nature Publishing
The mouse cancer model 'Multi-Hit' allows for the evaluation of oncogene cooperativities in tumor development based on stochastic Cre-recombination events. Cells with cooperating oncogenes are positively selected and give rise to tumors. The approach..
Original Article: A mouse model to identify cooperating signaling pathways in cancer
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